lunes, 28 de octubre de 2019

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 October 28, 2019 
 Genomics 
 The latest genomics news from News-Medical 
 #ALT#Webinar: Single cell analysis with dropSeqPipe

Looking to analyze your single-cell RNA-Seq data in an easy and reproducible manner? Join the webinar with Sebastian Muller, a dropSeqPipe development contributor and bioinformatics expert, to find out more about the basics of dropSeqPipe, how to take control of your data quality, how to generate tailored graphical visualization to suit your need and also watch dropSeqPipe in action!

Register Now
 
   Novel viral vector improves gene therapy for sickle cell diseaseNovel viral vector improves gene therapy for sickle cell disease
 
Researchers at the National Institutes of Health (NIH) have developed a unique, improved viral vector to use in gene therapy for sickle cell disease. Using animal models, the new vector was shown to support the transfer of corrective genes into bone marrow stem cells up to ten times more efficiently than current vectors.
 
   Uses of CRISPR/Cas Biosensing SystemsUses of CRISPR/Cas Biosensing Systems
 
The CRISPR/Cas 9 system is being widely employed for editing genes in mammalian systems. However, recently, the Cas9 enzyme has demonstrated potential as a biosensor, and various Cas effectors are now being applied to molecular diagnostics.
 
 A Guide to Understanding Gene Expression
 
A Guide to Understanding Gene ExpressionBeing able to analyze gene expression patterns is essential for understanding protein function, biological pathways and cellular responses to external and internal stimuli. This article aims to provide a brief overview of the processes that underpin gene expression and the techniques that can be used to quantify the expression of specific genes.
 
 
 Researchers completely eliminate all traces of HIV from infected mice
 
Researchers completely eliminate all traces of HIV from infected miceFor the first time, researchers have successfully removed HIV-1 DNA from the genomes of living animals, a critical step towards a potential cure for the disease. The team initially used drugs to suppress viral replication in mice. They then used the gene-editing tool CRISPR-Cas9 to eliminate viral DNA that had hidden itself in immune cells.
 
 
 Scientists use ultrasound to detect active genes in live cells
 
Scientists use ultrasound to detect active genes in live cellsA startling new study published in the journal Science shows that ultrasound can help scientists to understand whether specific genes are in the active or inactive state in live cells. This incredible feat promises to transform the way scientists examine a host of living cell activities, ranging from the growth of tumors to neuron function.
 
 
 Scientists successfully create age-resistant mice with hyper-long telomeres
 
Scientists successfully create age-resistant mice with hyper-long telomeresResearchers at the Spanish National Cancer Research Centre (CNIO) have shown that it is possible to extend the life of mice, without using any gene modifying technologies. The finding is the result of a study launched some years ago that aimed to investigate mice with hyper-long telomeres.
 
 
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