UBR-box containing protein, UBR5, is over-expressed in human lung adenocarcinoma and is a potential therapeutic target | BMC Cancer | Full Text

UBR-box containing protein, UBR5, is over-expressed in human lung adenocarcinoma and is a potential therapeutic target | BMC Cancer | Full Text

UBR-box containing protein, UBR5, is over-expressed in human lung adenocarcinoma and is a potential therapeutic target

N-end rule ubiquitination pathway is known to be disrupted in many diseases, including cancer. UBR5, an E3 ubiquitin ligase, is mutated and/or overexpressed in human lung cancer cells suggesting its pathologic...

Authors:Kumar Saurabh, Parag P. Shah, Mark A. Doll, Leah J. Siskind and Levi J. Beverly

Citation:BMC Cancer 2020 20:824

Content type:Research article

 

Published on: 31 August 2020

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