Caption: DNA (blue) loops around nucleosomes (gray) and is bound by transcription factors (red), proteins that switch genes on and off and act in a tissue-specific manner. When cells die, enzymes (scissors) chop up areas between the nucleosomes and transcription factors, releasing DNA fragments in unique patterns. By gathering the released DNA fragments in blood, researchers can tell which types of cells produced them.
Credit: Shendure Lab/University of Washington
Credit: Shendure Lab/University of Washington
From HuGE Literature Finder Database
This database contains published literature on genetic associations and other human genome epidemiology
- Unique Genetic Profiles from Cerebrospinal Fluid Cell-free DNA in Leptomeningeal Metastases of EGFR-mutant Non-Small Cell Lung Cancer: A New Medium of Liquid Biopsy.
Annals of oncology : official journal of the European Society for Medical Oncology 2018 Jan .
Li Y S, Jiang B Y, Yang J J, Zhang X C, Zhang Z, Ye J Y, Zhong W Z, Tu H Y, Chen H J, Wang Z, Xu C R, Wang B C, Du H J, Chuai S, Han-Zhang H, Su J, Zhou Q, Yang X N, Guo W B, Yan H H, Liu Y H, Yan L X, Huang B, Zheng M M, Wu Y - Genomic landscape of cell-free DNA in patients with colorectal cancer.
Cancer discovery 2017 Dec .
Strickler John H, Loree Jonathan M, Ahronian Leanne G, Parikh Aparna R, Niedzwiecki Donna, Pereira Allan Andresson Lima, McKinney Matthew, Korn W Michael, Atreya Chloe E, Banks Kimberly C, Nagy Rebecca J, Meric-Bernstam Funda, Lanman Richard B, Talasaz AmirAli, Tsigelny Igor F, Corcoran Ryan B, Kopetz Sco - Improved EGFR mutation detection using combined exosomal RNA and circulating tumor DNA in NSCLC patient plasma.
Annals of oncology : official journal of the European Society for Medical Oncology 2017 Dec .
Krug A K, Enderle D, Karlovich C, Priewasser T, Bentink S, Spiel A, Brinkmann K, Emenegger J, Grimm D G, Castellanos-Rizaldos E, Goldman J W, Sequist L V, Soria J-C, Camidge D R, Gadgeel S M, Wakelee H A, Raponi M, Noerholm M, Skog - Cell-Free DNA and Circulating Tumor Cells: Comprehensive liquid biopsy analysis in Advanced Breast Cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2017 Nov .
Rossi Giovanna, Mu Zhaomei, Rademaker Alfred, Austin Laura, Strickland Kimberly S, Lima Barros Costa Ricardo, Nagy Rebecca, Zagonel Vittorina, Taxter Timothy J, Behdad Amir, Wehbe Firas H, Platanias Leonidas C, Gradishar William, Cristofanilli Massi - Multiple Hotspot Mutations Scanning by Single Droplet Digital PCR.
Clinical chemistry 2017 Nov .
Decraene Charles, Silveira Amanda, Bidard François-Clément, Vallee Audrey, Michel Marc, Melaabi Samia, Vincent-Salomon Anne, Saliou Adrien, Houy Alexandre, Milder Maud, Lantz Olivier, Ychou Marc, Denis Marc G, Pierga Jean-Yves, Stern Marc-Henri, Proudhon Charlot
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