Mendelian randomization [NEW TOPIC PAGE]

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Last Posted: Feb 11, 2020

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• Using human genetics to understand the disease impacts of testosterone in men and women
  KS Ruth et al, Nature Medicine, February 10, 2020
• Summary-data-based mendelian randomization reveals druggable targets for multiple sclerosis
  BM Jacobs et al, BioRXIV preprints, January 25, 2020
• Genetically-predicted life-long lowering of low-density lipoprotein cholesterol is associated with decreased frailty: A Mendelian randomization study in UK biobank.
  Wang Qi et al. EBioMedicine 2019 Jul 45487-494
• Diabetes mellitus, glycemic traits, and cerebrovascular disease: a Mendelian randomization study
  MC Georgakis et al, MedRXIV, December 30, 2019
• The causal role of circulating vitamin D concentrations in human complex traits and diseases: a large-scale Mendelian randomization study
  X Jiang et al, BIOXIV, December 2019
• The causes and consequences of Alzheimer's disease: A Mendelian randomization analysis
  BIORXIV, December 2019
• Proxy gene-by-environment Mendelian randomization study confirms a causal effect of maternal smoking on offspring birthweight, but little evidence of long-term influences on offspring health.
  Yang Qian et al. International journal of epidemiology 2019 Dec
• Homogeneity in the association of body mass index with type 2 diabetes across the UK Biobank: A Mendelian randomization study.
  Wainberg Michael et al. PLoS medicine 2019 Dec (12) e1002982
• The gene-based hack that is revolutionizing epidemiology
  D Adam, Nature News, December 10, 2019
• Phenome-wide Mendelian randomization mapping the influence of the plasma proteome on complex diseases
  J Zheng et al, BIORXIV, December 2019

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