lunes, 3 de febrero de 2020

Parkinson's disease - a series of reviews

Parkinson's disease - a series of reviews



Parkinson's Disease - a series of reviews

New Content ItemThis series, guest-edited by Mark Cookson and Ted Dawson, collates reviews surrounding the topic of Parkinson's Disease to provide a comprehensive oversight of recent advances and viewpoints across the field.

All submissions have been subject to Molecular Neurodegeneration's standard peer review process, and articles will be added to this series throughout the coming year. 
  1. Since the discovery of leucine-rich repeat kinase 2 (LRRK2) as a protein that is likely central to the aetiology of Parkinson’s disease, a considerable amount of work has gone into uncovering its basic cellula...
    Authors:Daniel C. Berwick, George R. Heaton, Sonia Azeggagh and Kirsten Harvey
    Citation:Molecular Neurodegeneration 2019 14:49
    Content type:Review
    Published on: 
  2. Mutations in GBA1, the gene encoding the lysosomal enzyme glucocerebrosidase, are among the most common known genetic risk factors for the development of Parkinson disease and related synucleinopathies. A great d...
    Authors:Jenny Do, Cindy McKinney, Pankaj Sharma and Ellen Sidransky
    Citation:Molecular Neurodegeneration 2019 14:36
    Content type:Review
    Published on: 
  3. A full understanding of Parkinson’s Disease etiopathogenesis and of the causes of the preferential vulnerability of nigrostriatal dopaminergic neurons is still an unsolved puzzle. A multiple-hit hypothesis has...
    Authors:Anna Masato, Nicoletta Plotegher, Daniela Boassa and Luigi Bubacco
    Citation:Molecular Neurodegeneration 2019 14:35
    Content type:Review
    Published on: 
  4. An emerging picture suggests that glial cells’ loss of beneficial roles or gain of toxic functions can contribute to neurodegenerative conditions. Among glial cells, microglia and astrocytes have been shown to...
    Authors:Marie-Eve Tremblay, Mark R. Cookson and Laura Civiero
    Citation:Molecular Neurodegeneration 2019 14:16
    Content type:Review
    Published on: 
  5. Dementia with Lewy bodies (DLB) is an age-associated neurodegenerative disorder producing progressive cognitive decline that interferes with normal life and daily activities. Neuropathologically, DLB is charac...
    Authors:Tiago Fleming Outeiro, David J. Koss, Daniel Erskine, Lauren Walker, Marzena Kurzawa-Akanbi, David Burn, Paul Donaghy, Christopher Morris, John-Paul Taylor, Alan Thomas, Johannes Attems and Ian McKeith
    Citation:Molecular Neurodegeneration 2019 14:5
    Content type:Review
    Published on: 

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