Tau-tubulin kinase 1 and amyloid-β peptide induce phosphorylation of collapsin response mediator protein-2 and enhance neurite degeneration in Alzheimer disease mouse models | Acta Neuropathologica Communications | Full Text

Tau-tubulin kinase 1 and amyloid-β peptide induce phosphorylation of collapsin response mediator protein-2 and enhance neurite degeneration in Alzheimer disease mouse models | Acta Neuropathologica Communications | Full Text

Tau-tubulin kinase 1 and amyloid-β peptide induce phosphorylation of collapsin response mediator protein-2 and enhance neurite degeneration in Alzheimer disease mouse models

The accumulation of phosphorylated tau protein (pTau) in the entorhinal cortex (EC) is the earliest tau pathology in Alzheimer’s disease (AD). Tau tubulin kinase-1 (TTBK1) is a neuron-specific tau kinase and e...

Authors:Seiko Ikezu, Kaitlin L. Ingraham Dixie, Lacin Koro, Takashi Watanabe, Kozo Kaibuchi and Tsuneya Ikezu

Citation:Acta Neuropathologica Communications 2020 8:12

Content type:Research

Published on: 4 February 2020

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