LUNG CANCER WEEKLY UPDATE: August 4-11, 2016 || Public Health Genomics Knowledge Base (v1.2)

Public Health Genomics Knowledge Base (v1.2)



August 4-11, 2016


Last Updated: Aug 05, 2016

• Total and mutated EGFR quantification in cell-free DNA from non-small cell lung cancer patients detects tumor heterogeneity and presents prognostic value.
  Alegre E, et al. Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2016 7
• TGF-?1 rs1982073 polymorphism contributes to radiation pneumonitis in lung cancer patients: a meta-analysis.
  Shen Ze-Tian, et al. Journal of cellular and molecular medicine 2016 7
• Clinical efficacy of first-generation EGFR-TKIs in patients with advanced non-small-cell lung cancer harboring EGFR exon 20 mutations.
  Chen Dan, et al. OncoTargets and therapy 2016 0 4181-6
• PD-L1 expression in non-small cell lung cancer: Correlations with genetic alterations.
  Scheel Andreas H, et al. Oncoimmunology 2016 5 (5) e1131379
• The genetic variations in DNA repair genes ERCC2 and XRCC1 were associated with the overall survival of advanced non-small-cell lung cancer patients.
  Wang Suhan, et al. Cancer medicine 2016 7
• A randomized phase 2 study comparing the combination of ficlatuzumab and gefitinib with gefitinib alone in Asian patients with advanced stage pulmonary adenocarcinoma.
  Kam Mok Tony Shu, et al. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2016 7
• ALK positivity on pleuroscopic pleural biopsy in lung adenocarcinoma.
  Vaidya Preyas J, et al. Journal of cancer research and therapeutics 0 0 (2) 1090-2
• An efficient method to genotype the polymorphisms of cholinergic nicotinic receptor subunit genes and their associations with COPD onset risk.
  Zhao Zhuxiang, et al. Experimental lung research 2016 6 (5) 267-74
• Association between XPA Gene rs1800975 Polymorphism and Susceptibility to Lung Cancer: A meta-analysis.
  Liu Xin, et al. The clinical respiratory journal 2016 7
• Association of GSTM1 and GSTT1 deletion with lung cancer development in Pakistani population.
  Masood Nosheen, et al. Journal of cancer research and therapeutics 0 0 (2) 731-4
• Frequency of epidermal growth factor receptor mutations in Jordanian lung adenocarcinoma patients at diagnosis.
  Obeidat Natheir, et al. Journal of cancer research and therapeutics 0 0 (2) 616-9
• Higher frequency but random distribution of EGFR mutation subtypes in familial lung cancer patients.
  Hsu Kuo-Hsuan, et al. Oncotarget 2016 7
• Plasma MiRNA alterations between NSCLC patients harboring Del19 and L858R EGFR mutations.
  Ma Yihan, et al. Oncotarget 2016 7
• rs61764370 polymorphism of Kras and risk of cancer in Caucasian population: A meta-analysis.
  Zhang Shi-Yan, et al. Journal of cancer research and therapeutics 0 0 (2) 699-704
• Survival of Patients with Advanced Non-Small Cell Lung Cancer Enrolled in Clinical Trials.
  Arrieta Oscar, et al. Oncology 2016 7

• CDC Information (2)
• CDC-Authored Pub (8)

• Human (30)
• Pathogen (0)

• Human (3878)
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• Human (61)
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• Guidelines (8)
• Tier Table (4)
• Synthesis (10)

• Huamn (4)
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Relevant Resources

• Cancer Genomics and Epidemiology Navigator (CGEN)
• Genetics and Genomics Competencies Center (G2C2)
• NIH Genetic Testing Registry
• NIH MedGen Database
• Online Mendelian Inheritance in Man (OMIM)
• PharmGKB