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From PubMed Clinical Queries

PubMed Clinical Queries is an utility offered by PubMed to search scientific literature in specific clinical research areas

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• Search PubMed Clinical Queries for "Brca" 

Results: 5 of 882

• Quality of life in patients with recurrent ovarian cancer treated with niraparib versus placebo (ENGOT-OV16/NOVA): results from a double-blind, phase 3, randomised controlled trial.
  Oza AM, Matulonis UA, Malander S, Hudgens S, Sehouli J, Del Campo JM, Berton-Rigaud D, Banerjee S, Scambia G, Berek JS, et al.Lancet Oncol. 2018 Jul 16; . Epub 2018 Jul 16.
• Clinical outcomes of adolescents and young adults with advanced solid tumours participating in phase I trials.
  Sundar R, McVeigh T, Dolling D, Petruckevitch A, Diamantis N, Ang JE, Chenard-Poiriér M, Collins D, Lim J, Ameratunga M, et al.Eur J Cancer. 2018 Jul 16; 101:55-61. Epub 2018 Jul 16.
• Description of Genetic Variants in <i>BRCA</i> Genes in Mexican Patients with Ovarian Cancer: A First Step towards Implementing Personalized Medicine.
  Delgado-Balderas JR, Garza-Rodriguez ML, Gomez-Macias GS, Barboza-Quintana A, Barboza-Quintana O, Cerda-Flores RM, Miranda-Maldonado I, Vazquez-Garcia HM, Valdez-Chapa LD, Antonio-Macedo M, et al.Genes (Basel). 2018 Jul 11; 9(7). Epub 2018 Jul 11.
• Single-agent PARP inhibitors for the treatment of patients with <i>BRCA</i>-mutated HER2-negative metastatic breast cancer: a systematic review and meta-analysis.
  Poggio F, Bruzzone M, Ceppi M, Conte B, Martel S, Maurer C, Tagliamento M, Viglietti G, Del Mastro L, de Azambuja E, et al.ESMO Open. 2018; 3(4):e000361. Epub 2018 Jun 20.
• Change in inflammatory biomarkers and adipose tissue in BRCA1/2+ breast cancer survivors following a year-long lifestyle modification program.
  Sturgeon KM, Foo WY, Heroux ML, Schmitz K.Cancer Prev Res (Phila). 2018 Jun 20; . Epub 2018 Jun 20.

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This column displays citations filtered to a specific clinical study category and scope. These search filters were developed by Haynes RB et al. See more filter information.

Systematic Reviews

Results: 5 of 146

• Single-agent PARP inhibitors for the treatment of patients with <i>BRCA</i>-mutated HER2-negative metastatic breast cancer: a systematic review and meta-analysis.
  Poggio F, Bruzzone M, Ceppi M, Conte B, Martel S, Maurer C, Tagliamento M, Viglietti G, Del Mastro L, de Azambuja E, et al.ESMO Open. 2018; 3(4):e000361. Epub 2018 Jun 20.
• Niraparib for the treatment of ovarian cancer.
  Essel KG, Moore KN.Expert Rev Anticancer Ther. 2018 Aug; 18(8):727-733. Epub 2018 Jul 2.
• A systematic review on the frequency of BRCA promoter methylation in breast and ovarian carcinomas of BRCA germline mutation carriers: Mutually exclusive, or not?
  Vos S, van Diest PJ, Moelans CB.Crit Rev Oncol Hematol. 2018 Jul; 127:29-41. Epub 2018 May 14.
• Platinum-based neoadjuvant chemotherapy in triple-negative breast cancer: a systematic review and meta-analysis.
  Poggio F, Bruzzone M, Ceppi M, Pondé NF, La Valle G, Del Mastro L, de Azambuja E, Lambertini M.Ann Oncol. 2018 Jul 1; 29(7):1497-1508.
• How shall we treat early triple-negative breast cancer (TNBC): from the current standard to upcoming immuno-molecular strategies.
  Park JH, Ahn JH, Kim SB.ESMO Open. 2018; 3(Suppl 1):e000357. Epub 2018 May 3.

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This column displays citations for systematic reviews, meta-analyses, reviews of clinical trials, evidence-based medicine, consensus development conferences, and guidelines. See filter information or additional related sources.

Medical Genetics

Topic:AllDiagnosisDifferential DiagnosisClinical DescriptionManagementGenetic CounselingMolecular GeneticsGenetic Testing

Results: 5 of 2936

• Quality of life in patients with recurrent ovarian cancer treated with niraparib versus placebo (ENGOT-OV16/NOVA): results from a double-blind, phase 3, randomised controlled trial.
  Oza AM, Matulonis UA, Malander S, Hudgens S, Sehouli J, Del Campo JM, Berton-Rigaud D, Banerjee S, Scambia G, Berek JS, et al.Lancet Oncol. 2018 Jul 16; . Epub 2018 Jul 16.
• The yield of full BRCA1/2 genotyping in Israeli high-risk breast/ovarian cancer patients who do not carry the predominant mutations.
  Barnes-Kedar I, Bernstein-Molho R, Ginzach N, Hartmajer S, Shapira T, Magal N, Kalis ML, Peretz T, Shohat M, Basel-Salmon L, et al.Breast Cancer Res Treat. 2018 Jul 16; . Epub 2018 Jul 16.
• Breast Cancer Genetics and Indications for Prophylactic Mastectomy.
  Krontiras H, Farmer M, Whatley J.Surg Clin North Am. 2018 Aug; 98(4):677-685. Epub 2018 May 30.
• Migrating the SNP array-based homologous recombination deficiency measures to next generation sequencing data of breast cancer.
  Sztupinszki Z, Diossy M, Krzystanek M, Reiniger L, Csabai I, Favero F, Birkbak NJ, Eklund AC, Syed A, Szallasi Z.NPJ Breast Cancer. 2018; 4:16. Epub 2018 Jul 2.
• The neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios predict efficacy of platinum-based chemotherapy in patients with metastatic triple negative breast cancer.
  Vernieri C, Mennitto A, Prisciandaro M, Huber V, Milano M, Rinaldi L, Cona MS, Maggi C, Ferrari B, Manoukian S, et al.Sci Rep. 2018 Jun 7; 8(1):8703. Epub 2018 Jun 7.

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This column displays citations pertaining to topics in medical genetics. See more filter information.