Cancer Genomics - Cancer PHGKB -

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Cancer Genomics

- Cancer PHGKB -

What's New

Last Posted: Aug 16, 2018

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• Talazoparib in Patients with Advanced Breast Cancer and a Germline BRCA Mutation.  
  Litton Jennifer K et al. The New England journal of medicine 2018 Aug
• A precision therapy against cancers driven by KIT/PDGFRA mutations.  
  Evans Erica K et al. Science translational medicine 2017 Nov 9(414)
• Adrenocortical carcinoma (ACC): When and why should we consider germline testing?  
  Petr Elisabeth Joye et al. Presse medicale (Paris, France : 1983) 2018 Aug
• Biological material collection to advance translational research and treatment of children with CNS tumours: position paper from the SIOPE Brain Tumour Group. 
  Rutkowski Stefan et al. The Lancet. Oncology 2018 Aug 19(8) e419-e428
• Circulating Tumor DNA Reveals Clinically Actionable Somatic Genome of Metastatic Bladder Cancer.  
  Vandekerkhove Gillian et al. Clinical cancer research : an official journal of the American Association for Cancer Research 2017 Nov 23(21) 6487-6497
• Circulating tumoral DNA: Preanalytical validation and quality control in a diagnostic laboratory.  
  Nikolaev Sergey et al. Analytical biochemistry 2018 54234-39
• Clues to Your Health Are Hidden at 6.6 Million Spots in Your DNA With a sophisticated new algorithm, scientists have found a way to forecast an individual’s risks for five deadly diseases.  
  G Kolata, New York Times, August 13, 2018
• Cost-effectiveness and safety of the molecular targeted drugs afatinib, gefitinib and erlotinib as first-line treatments for patients with advanced EGFR mutation-positive non-small-cell lung cancer.  
  Kimura M et al. Molecular and clinical oncology 2018 Aug 9(2) 201-206
• EGFR Mutation Testing of non-squamous NSCLC: Impact and Uptake during Implementation of Testing Guidelines in a Population-Based Registry Cohort from Northern New Zealand.  
  McKeage Mark et al. Targeted oncology 2017 12(5) 663-675
• Evaluating somatic tumor mutation detection without matched normal samples. 
  Teer Jamie K et al. Human genomics 2017 Sep 11(1) 22