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Cancer & Metabolism

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1. Content Type:Research

     |  17 August 2018

   Hexokinase 2 is dispensable for T cell-dependent immunity

   Authors:Manan M. Mehta, Samuel E. Weinberg, Elizabeth M. Steinert, Krishan Chhiba, Carlos Alberto Martinez, Peng Gao, Harris R. Perlman, Paul Bryce, Nissim Hay and Navdeep S. Chandel
2. Content Type:Research

     |  10 July 2018

   Inflammation-induced DNA methylation of DNA polymerase gamma alters the metabolic profile of colon tumors

   Authors:Ashley R. Maiuri, Hongde Li, Barry D. Stein, Jason M. Tennessen and Heather M. O’Hagan
3. Content Type:Research

     |  28 June 2018

   A precision therapeutic strategy for hexokinase 1-null, hexokinase 2-positive cancers

   Authors:Shili Xu, Arthur Catapang, Daniel Braas, Linsey Stiles, Hanna M. Doh, Jason T. Lee, Thomas G. Graeber, Robert Damoiseaux, Orian Shirihai and Harvey R. Herschman
4. Content Type:Research

     |  11 June 2018

   Beta-hydroxybutyrate (3-OHB) can influence the energetic phenotype of breast cancer cells, but does not impact their proliferation and the response to chemotherapy or radiation

   Authors:Catharina Bartmann, Sudha R. Janaki Raman, Jessica Flöter, Almut Schulze, Katrin Bahlke, Jana Willingstorfer, Maria Strunz, Achim Wöckel, Rainer J. Klement, Michaela Kapp, Cholpon S. Djuzenova, Christoph Otto and Ulrike Kämmerer
5. Content Type:Research

     |  31 May 2018

   Isoform-specific deletion of PKM2 constrains tumor initiation in a mouse model of soft tissue sarcoma

   Authors:Talya L. Dayton, Vasilena Gocheva, Kathryn M. Miller, Arjun Bhutkar, Caroline A. Lewis, Roderick T. Bronson, Matthew G. Vander Heiden and Tyler Jacks

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