Transcranial ultrasound stimulation and its applications in neurosciences

Transcranial ultrasound stimulation and its applications in neurosciences

Transcranial ultrasound stimulation (TUS) is an emerging technique that can noninvasively excite or inhibit neural activity in targeted brain regions by delivery of pulsed ultrasonic waves. TUS is therefore a valuable tool to modulate specific neuronal pathways or nuclei in both the basic and clinical neurosciences, and may have therapeutic potential in neurological diseases such as Alzheimer's Disease, epilepsy, and stroke. Our latest guest-edited collection brings together recent research published in BMC Neuroscience concerning technological advances, potential applications, and therapeutic effects, of transcranial ultrasound stimulation.

1. Content Type:Research Article

   Non-invasive measurement of hemodynamic change during 8 MHz transcranial focused ultrasound stimulation using near-infrared spectroscopy

   Transcranial focused ultrasound (tFUS) attracts wide attention in neuroscience as an effective noninvasive approach to modulate brain circuits. In spite of this, the effects of tFUS on the brain is still uncle...

   Authors:Evgenii Kim, Eloise Anguluan, Sangyeon Youn, Jihun Kim, Jae Youn Hwang and Jae Gwan Kim

   Citation:BMC Neuroscience 2019 20:12

   Published on: 18 March 2019

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2. Content Type:Research Article

   Inhibitory effect of ultrasonic stimulation on the voltage-dependent potassium currents in rat hippocampal CA1 neurons

   Transcranial ultrasonic stimulation is a novel noninvasive tool for neuromodulation, and has high spatial resolution and deep penetration. Although it can increase excitation of neurons, its effects on neuron ...

   Authors:Kun Cui, Shuai Zhang, Jinyao Sun, Xueying Zhang, Chong Ding and Guizhi Xu

   Citation:BMC Neuroscience 2019 20:3

   Published on: 5 January 2019

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3. Content Type:Research Article

   The effect of anesthetic dose on the motor response induced by low-intensity pulsed ultrasound stimulation

   Low-intensity pulsed ultrasound stimulation (LIPUS) has been proven to be a noninvasive method with high spatial resolution and deep penetration. Previous studies have qualitatively demonstrated that the elect...

   Authors:Yi Yuan, Xingran Wang, Jiaqing Yan and Xiaoli Li

   Citation:BMC Neuroscience 2018 19:78

   Published on: 3 December 2018

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4. Content Type:Research Article

   Effect of pulsed transcranial ultrasound stimulation at different number of tone-burst on cortico-muscular coupling

   Pulsed transcranial ultrasound stimulation (pTUS) can modulate the neuronal activity of motor cortex and elicit muscle contractions. Cortico-muscular coupling (CMC) can serve as a tool to identify interaction ...

   Authors:Ping Xie, Sa Zhou, Xingran Wang, Yibo Wang and Yi Yuan

   Citation:BMC Neuroscience 2018 19:60

   Published on: 3 October 2018

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5. Content Type:Research Article

   Transcranial focused ultrasound stimulation of motor cortical areas in freely-moving awake rats

   Low-intensity transcranial focused ultrasound (tFUS) has emerged as a new non-invasive modality of brain stimulation with the potential for high spatial selectivity and penetration depth. Anesthesia is typical...

   Authors:Wonhye Lee, Phillip Croce, Ryan W. Margolin, Amanda Cammalleri, Kyungho Yoon and Seung-Schik Yoo

   Citation:BMC Neuroscience 2018 19:57

   Published on: 19 September 2018

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6. Content Type:Research Article

   Effects of transcranial focused ultrasound on human primary motor cortex using 7T fMRI: a pilot study

   Transcranial focused ultrasound (tFUS) is a new non-invasive neuromodulation technique that uses mechanical energy to modulate neuronal excitability with high spatial precision. tFUS has been shown to be capab...

   Authors:Leo Ai, Priya Bansal, Jerel K. Mueller and Wynn Legon

   Citation:BMC Neuroscience 2018 19:56

   Published on: 14 September 2018

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7. Content Type:Research Article

   Simultaneous acoustic stimulation of human primary and secondary somatosensory cortices using transcranial focused ultrasound

   Transcranial focused ultrasound (FUS) is gaining momentum as a novel non-invasive brain stimulation method, with promising potential for superior spatial resolution and depth penetration compared to transcrani...

   Authors:Wonhye Lee, Yong An Chung, Yujin Jung, In-Uk Song and Seung-Schik Yoo

   Citation:BMC Neuroscience 2016 17:68

   Published on: 26 October 2016

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