What is Formoline L112?
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In today’s market many weight aid loss remedies are being advertised with only a few registered as medical devices. One popular, well-known and registered weight loss aid is called formoline L112.
Formoline L112 is a linear polysaccharide (chitosan) with a low molecular weight. It consists of a ß-1,4-polymer of D-glucosamine and N-acetyl-D-glucosamine, which are derived from shellfish. It is part of a subgroup of polyglucosamines and registered as a class III medical device in Germany.
The main effect of formoline L112 is to limit the absorption of dietary fat absorbed, aid weight loss and weight maintenance, and to lower high cholesterol levels in the blood.
The manufacturer recommends that persons desiring weight loss take 2 tablets twice daily for weight loss or 1 tablet twice daily for weight management. The pills are designed to be taken toward the end of the two highest fat meals of the day.
Effectiveness of formoline L112 for losing weight
Several studies have shown modest weight loss and cholesterol lowering with formoline L112 use. One study showed that those taking formoline L112 for 25 weeks lost 1.8 kg more weight than those taking placebo. However, the participants were not followed beyond this time frame to see if the weight loss persisted over time.
In the study by Cnubben in 2016, the fat absorption from the GI tract to the circulation and exposure to free fatty acids were reduced, which may benefit overweight persons.
A review from 2018 by Cornelli concluded that polyglucosamine L112 binds to lipids and effectively reduces omental fat mass.
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