COVID-19 GPH|Home|PHGKB

COVID-19 GPH|Home|PHGKB

 Spotlight

Racial disparities in COVID-19 mortality are driven by unequal infection risks.
J Zelner et al, MEDRXIV, September 11, 2020

We used individual-level COVID-19 incidence and mortality data from Michigan to estimate age-specific incidence and mortality rates by race/ethnic group. The findings suggest that well-documented racial disparities in mortality in hard-hit settings, are driven primarily by variation in household, community and workplace exposure rather than case-fatality rates.

Socio-economic disparities and COVID-19 in the USA
A Paul et al, MEDRXIV, September 11, 2020

We correlate the COVID-19 prevalence and death rate with data from the US Census Bureau and point out how the spreading patterns of the disease show asymmetries in urban and rural areas separately and is preferentially affecting the counties where a large fraction of the population is non-white.

Exploring the structural distribution of genetic variation in SARS-CoV-2 with the COVID-3D online resource
S Portelli et al, Nature Genetics, September 10, 2020

Despite the novelty of the virus, global sequencing efforts have already identified genomic variation across isolates. To enable easy exploration and spatial visualization of the potential implications of SARS-CoV-2 mutations in infection, host immunity and drug development, we have developed COVID-3D.

The UCSC SARS-CoV-2 Genome Browser
JD Fernandes et al, Nature Genetics, September 10, 2020

The browser is an adaptation of our popular genome-browser visualization tool for this virus, containing many annotation tracks and new features, including conservation with similar viruses, immune epitopes, RT–PCR and sequencing primers and CRISPR guides.