From tobacco smoking to cancer mutational signature: a mediation analysis strategy to explore the role of epigenetic changes | BMC Cancer | Full Text

From tobacco smoking to cancer mutational signature: a mediation analysis strategy to explore the role of epigenetic changes | BMC Cancer | Full Text

From tobacco smoking to cancer mutational signature: a mediation analysis strategy to explore the role of epigenetic changes

Tobacco smoking is associated with a unique mutational signature in the human cancer genome. It is unclear whether tobacco smoking-altered DNA methylations and gene expressions affect smoking-related mutationa...

Authors:Zhishan Chen, Wanqing Wen, Qiuyin Cai, Jirong Long, Ying Wang, Weiqiang Lin, Xiao-ou Shu, Wei Zheng and Xingyi Guo

Citation:BMC Cancer 2020 20:880

Content type:Research article

 

Published on: 14 September 2020

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