Affiliated with
Improvements across a range of patient-reported domains with fremanezumab treatment: results from a patient survey study
The long-term safety and efficacy of fremanezumab were evaluated in a 52-week extension study (NCT02638103). Patient satisfaction with fremanezumab, dosing preferences, and patient-reported outcomes were asses...21:109The Journal of Headache and Pain 2020The prevalence of headache disorders in children and adolescents in Ethiopia: a schools-based study
The Global Burden of Disease (GBD) study establishes headache as the second-highest cause of disability worldwide. Because most headache data in GBD are from adults, leading to underestimation of headache-attr...21:108The Journal of Headache and Pain 2020The prevalence of headache disorders in children and adolescents in Mongolia: a nationwide schools-based study
The Global Campaign against Headache collects data from children (7–11 years) and adolescents (12–17 years) both to inform health and education policies and to contribute to the Global Burden of Disease (GBD) ...21:107The Journal of Headache and Pain 2020Optogenetic stimulation of the motor cortex alleviates neuropathic pain in rats of infraorbital nerve injury with/without CGRP knock-down
Previous studies have reported that electrical stimulation of the motor cortex is effective in reducing trigeminal neuropathic pain; however, the effects of optical motor cortex stimulation remain unclear.21:106The Journal of Headache and Pain 2020Altered levels of salivary and plasma pain related markers in temporomandibular disorders
Different pain syndromes may be characterized by different profiles of mediators reflecting pathophysiological differences, and these alterations may be measured in a simple saliva sample. The aims of the curr...21:105The Journal of Headache and Pain 2020Correction to: Impact of migraine on workplace productivity and monetary loss: a study of employees in banking sector in Malaysia
An amendment to this paper has been published and can be accessed via the original article.21:104The Journal of Headache and Pain 2020Gut microbiota regulates neuropathic pain: potential mechanisms and therapeutic strategy
Neuropathic pain (NP) is a sustained and nonreversible condition characterized by long-term devastating physical and psychological damage. Therefore, it is urgent to identify an effective treatment for NP. Unf...21:103The Journal of Headache and Pain 2020Conversion from chronic to episodic migraine in patients treated with erenumab: real-life data from an Italian region
Most patients treated with erenumab in clinical practice have chronic migraine (CM). We assessed the rate and possible predictors of conversion from CM to episodic migraine (EM) in a real-life study.21:102The Journal of Headache and Pain 2020Trigeminal activation patterns evoked by chemical stimulation of the dura mater in rats
Although migraine is one of the most common primary headaches, its therapy is still limited in many cases. The use of animal models is crucial in the development of novel therapeutic strategies, but unfortunat...21:101The Journal of Headache and Pain 2020The status and high risk factors of severe psychological distress in migraine patients during nCOV-2019 outbreak in Southwest China: a cross-sectional study
Psychological distress is highly prevalent among migraineurs during public health emergencies. The coronavirus disease 2019 (nCOV-2019) has created mass panic in China due to its highly contagious by contact a...21:100The Journal of Headache and Pain 2020Economic consequences of migraine in Sweden and implications for the cost-effectiveness of onabotulinumtoxinA (Botox) for chronic migraine in Sweden and Norway
Migraine is a common and incapacitating condition, with severe impact on the quality of life (QoL) of the afflicted and their families, and negative economic consequences through decreased workforce participat...21:99The Journal of Headache and Pain 2020Mid- to late-life migraine diagnoses and risk of dementia: a national register-based follow-up study
Previous studies found an association between migraine and dementia, which are two leading causes of disability. However, these studies did not differentiate between migraine types and did not investigate all ...21:98The Journal of Headache and Pain 2020Migraine, obesity and body fat distribution – a population-based study
Obesity has been linked to an increased prevalence of migraine, and to increased migraine attack frequency, but several questions are left unanswered by previous studies. We examined the relationship between o...21:97The Journal of Headache and Pain 2020Modulation of mechanosensory vibrissal responses in the trigeminocervical complex by stimulation of the greater occipital nerve in a rat model of trigeminal neuropathic pain
Stimulation of the occipital or trigeminal nerves has been successfully used to treat chronic refractory neurovascular headaches such as migraine or cluster headache, and painful neuropathies. Convergence of t...21:96The Journal of Headache and Pain 2020Efficacy and safety of erenumab in women with a history of menstrual migraine
We performed a post hoc, subgroup analysis of a phase 3, randomized, double-blind, placebo-controlled study of erenumab for prevention of episodic migraine (STRIVE) to determine the efficacy and safety of eren...21:95The Journal of Headache and Pain 2020Factors associated with the presence of headache in hospitalized COVID-19 patients and impact on prognosis: a retrospective cohort study
Headache is one of the most frequent neurologic manifestations in COVID-19. We aimed to analyze which symptoms and laboratory abnormalities were associated with the presence of headache and to evaluate if pati...21:94The Journal of Headache and Pain 2020Altered hypothalamic functional connectivity in post-traumatic headache after mild traumatic brain injury
Post-traumatic headache (PTH) is one of the most frequent symptoms following mild traumatic brain injury (mTBI). Neuroimaging studies implicate hypothalamic function connectivity (FC) disruption as an importan...21:93The Journal of Headache and Pain 2020Patients with chronic migraine without history of medication overuse are characterized by a peculiar white matter fiber bundle profile
We investigated intracerebral fiber bundles using a tract-based spatial statistics (TBSS) analysis of diffusion tensor imaging (DTI) data to verify microstructural integrity in patients with episodic (MO) and ...21:92The Journal of Headache and Pain 2020Cognitive and sensorimotor function in participants being treated for trigeminal neuralgia pain
Trigeminal neuralgia (TN) is an orofacial condition defined by reoccurring, spontaneous, short-lived but excruciating stabbing pain. Pharmacological interventions constitute the first-line treatment for TN, wi...21:91The Journal of Headache and Pain 2020Persistent post-traumatic headache: a migrainous loop or not? The preclinical evidence
According to the International Classification of Headache Disorders 3, post-traumatic headache (PTH) attributed to traumatic brain injury (TBI) is a secondary headache reported to have developed within 7 days ...21:90The Journal of Headache and Pain 2020Is there a reliable brain morphological signature for migraine?
Voxel-based morphometry (VBM) is a popular non-invasive magnetic resonance imaging technique to investigate brain gray matter (GM) differences between groups. Recently, two VBM studies in migraine have been pu...21:89The Journal of Headache and Pain 2020Influence of headache pain intensity and frequency on migraine-related disability in chronic migraine patients treated with OnabotulinumtoxinA
There is a need to establish which are the more relevant headache-related outcomes that have an impact on our patient’s lives to accurately evaluate treatment response in daily clinical practice.21:88The Journal of Headache and Pain 2020Neuropeptide FF receptor 2 inhibits capsaicin-induced CGRP Upregulation in mouse trigeminal ganglion
Stimulation of trigeminovascular pathway is widely used to establish the headache animal model. Headache is a common neurological disorder, in which symptomatic attacks are mediated by calcitonin-gene-related ...21:87The Journal of Headache and Pain 2020Acute sleep deprivation enhances susceptibility to the migraine substrate cortical spreading depolarization
Migraine is a common headache disorder, with cortical spreading depolarization (CSD) considered as the underlying electrophysiological event. CSD is a slowly propagating wave of neuronal and glial depolarizati...21:86The Journal of Headache and Pain 2020Administrative prevalence and incidence, characteristics and prescription patterns of patients with migraine in Germany: a retrospective claims data analysis
Migraine is a frequent headache disorder with high disease burden. The aims of this study were to determine the administrative prevalence and incidence of migraine in Germany; and to elucidate disease characte...21:85The Journal of Headache and Pain 2020Erenumab in highly therapy-refractory migraine patients: First German real-world evidence
Calcitonin gene related peptide (CGRP) monoclonal antibodies (mAB) are the first specific migraine prophylactic medication. Erenumab is the only CGRP mAB targeting the CGRP receptor. Clinical data regarding ef...21:84The Journal of Headache and Pain 2020P2X7 receptors exert a permissive effect on the activation of presynaptic AMPA receptors in rat trigeminal caudal nucleus glutamatergic nerve terminals
Purine receptors play roles in peripheral and central sensitization and are associated with migraine headache. We investigated the possibility that ATP plays a permissive role in the activation of AMPA recepto...21:83The Journal of Headache and Pain 2020Pitfals in recognition and management of trigeminal neuralgia
Trigeminal neuralgia (TN) is a severe, disabling form of painful cranial neuropathy. Even though TN has a typical clinical picture, diagnosis it is often missed or delayed in clinical practice. In order to inv...21:82The Journal of Headache and Pain 2020Migraine start, course and features over the cycle of combined hormonal contraceptive users with menstrual migraine – temporal relation to bleeding and hormone withdrawal: a prospective diary-based study
Many studies have described the features of menstrually-related migraines (MRM) in the natural cycle and the efficacy of prevention. MRM in combined hormonal contraceptive (CHC) users has scarcely been researc...21:81The Journal of Headache and Pain 2020Impact of primary headache disorder on quality of life among school students in Kuwait
Primary headache disorders have being increasingly reported in younger populations. They can have significant effects on their quality of life and academic achievement and may cause significant distress to the...21:80The Journal of Headache and Pain 2020Effect of age on pharmacokinetics, efficacy, and safety of galcanezumab treatment in adult patients with migraine: results from six phase 2 and phase 3 randomized clinical trials
Migraine clinical profile may change with age, making it necessary to verify that migraine treatments are equally safe and effective in older patients. These analyses evaluated the effects of patient age on th...21:79The Journal of Headache and Pain 2020The neuro-pathophysiology of temporomandibular disorders-related pain: a systematic review of structural and functional MRI studies
Chronic pain surrounding the temporomandibular joints and masticatory muscles is often the primary chief complaint of patients with temporomandibular disorders (TMD) seeking treatment. Yet, the neuro-pathophys...21:78The Journal of Headache and Pain 2020Addressing chronic persistent headaches after MTBI as a neuropathic pain state
An increasing number of patients with chronic persistent post-traumatic headache (PPTH) after mild traumatic brain injury (MTBI) are being referred to headache or pain specialists as conventional treatment opt...21:77The Journal of Headache and Pain 2020European headache federation consensus on the definition of resistant and refractory migraine
Despite advances in the management of headache disorders, some patients with migraine do not experience adequate pain relief with acute and preventive treatments. It is the aim of the present document to provi...21:76The Journal of Headache and Pain 2020Validation of an algorithm for automated classification of migraine and tension-type headache attacks in an electronic headache diary
This study evaluates the accuracy of an automated classification tool of single attacks of the two major primary headache disorders migraine and tension-type headache used in an electronic headache diary.21:75The Journal of Headache and Pain 2020Low-value care practice in headache: a Spanish mixed methods research study
Headache is one of the most prevalent diseases. The Global Burden of Disease Study ranks it as the seventh most common disease overall and the second largest neurological cause of disability in the world. The ...21:74The Journal of Headache and Pain 2020The prevalence of headache disorders in children and adolescents in Lithuania: a schools-based study
While the Global Burden of Disease (GBD) study reports headache disorders as the second-highest cause of disability worldwide, the headache data in GBD come very largely from adults. This national study in Lit...21:73The Journal of Headache and Pain 2020Calcitonin gene-related peptide facilitates sensitization of the vestibular nucleus in a rat model of chronic migraine
Vestibular migraine has recently been recognized as a novel subtype of migraine. However, the mechanism that relate vestibular symptoms to migraine had not been well elucidated. Thus, the present study investi...21:72The Journal of Headache and Pain 2020Lasmiditan mechanism of action – review of a selective 5-HT1F agonist
Migraine is a leading cause of disability worldwide, but it is still underdiagnosed and undertreated. Research on the pathophysiology of this neurological disease led to the discovery that calcitonin gene-rela...21:71The Journal of Headache and Pain 2020Sentinel headache as a warning symptom of ischemic stroke
There are no previous controlled studies of sentinel headache in ischemic stroke. The purpose of the present study was to evaluate the presence of such headache, its characteristics and possible risk factors a...21:70The Journal of Headache and Pain 2020Multidimensional assessment of the effects of erenumab in chronic migraine patients with previous unsuccessful preventive treatments: a comprehensive real-world experience
erenumab was safe and effective in clinical trials for the prevention of migraine. However, real-life data are still lacking. Here we report the clinical experience from an Italian real-world setting using ere...21:69The Journal of Headache and Pain 2020Impact of migraine on workplace productivity and monetary loss: a study of employees in banking sector in Malaysia
Productivity and monetary loss due to migraine in the workplace may be substantial. This study aimed to determine the impact of migraine on productivity and monetary lost among employees in the banking sectors...21:68The Journal of Headache and Pain 2020High sensitivity C-reactive protein and risk of migraine in a 11-year follow-up with data from the Nord-Trøndelag health surveys 2006–2008 and 2017–2019
Several previous studies have reported a cross-sectional association between elevated high sensitivity C-reactive protein (hs-CRP) and migraine. The aim of this population-based follow-up study was to investig...21:67The Journal of Headache and Pain 2020Short-term efficacy and safety of lasmiditan, a novel 5-HT1F receptor agonist, for the acute treatment of migraine: a systematic review and meta-analysis
Migraine has been recognized as one of common diseases in the world whose current treatment options are not ideal. Lasmiditan, an oral 5-hydroxytryptamine (HT)1F receptor agonist, appears more promising for the a...21:66The Journal of Headache and Pain 2020The fifth cranial nerve in headaches
The fifth cranial nerve is the common denominator for many headaches and facial pain pathologies currently known. Projecting from the trigeminal ganglion, in a bipolar manner, it connects to the brainstem and ...21:65The Journal of Headache and Pain 2020Genetics of migraine aura: an update
Migraine is a common brain disorder with a large genetic component. Of the two main migraine types, migraine with aura and migraine without aura, the genetic underpinning in the former is least understood. Giv...21:64The Journal of Headache and Pain 2020
No hay comentarios:
Publicar un comentario