What is a Non-Replicating Vaccine?

What is a Non-Replicating Vaccine?

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By Dr. Sanchari Sinha Dutta, Ph.D.Reviewed by Emily Henderson, B.Sc.

Non-replicating vaccines are based on recombinant viral vectors that are made replication non-competent, meaning that these vectors are sufficient to induce host immune responses but cannot replicate inside host cells.