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Immunology | Medical News | Medical Articles | Immunology |

	August 29, 2019
	Immunology
	The latest immunology news from News Medical

Webinar: Label-Free Live Cell Imaging Meets Immuno-Oncology

Dr. Mathieu Frechin, Head of Quantitative Biology at Nanolive will introduce you to our holotomographic microscopy and its implications in the field of Immuno-Oncology. During the webinar he will discuss the opportunities that are created by the usage of Nanolive’s label-free technology in the field of immune system research.

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			Defective immune signals could underlie some types of fatal heart disease John Hopkins researchers have come up with exciting evidence that confirms the role of abnormal immune signaling in some types of inflammatory heart disease. The research was recently published in the journal Cell Reports. In summary, it shows that among the two types of inflammatory cells called monocytes found in heart inflammation (myocarditis), the cytokine IL-17A inhibits the normal differentiation of the Ly6Clo type into macrophages.

			Gallstone formation may be driven by neutrophils For decades, doctors have known that gallstones assemble and grow from cholesterol and calcium crystals as the salts accumulate and stick together in bile – the yellowish-brown fluid that helps break down lipids in the small intestine. However, one hurdle that researchers have been unable to overcome in the development of new treatments is that they have not known how the calcium and cholesterol crystals stick together to form the stones.

	New antibiotics on the horizon as scientists discover a weakness in the cell wall of pathogenic bacteria Researchers have discovered a weak spot in the cell wall of pathogenic bacteria that could lead to the development of new antibiotics. This was a joint collaboration between researchers at the Hokkaido University of Japan, Duke University in the US and The Catholic University of Korea.

	Smartphone ‘virus scanner’ could help governments contain viral outbreaks Researchers have created and tested a miniature virus-scanning device for smartphones, which offers a more practical and financially feasible option for assessing the presence of biomarkers, a process that has traditionally required large and expensive equipment. Yoshihiro Minagawa from the University of Tokyo is behind the new device, called MobIP, which aims to make diagnosis and disease prevention easier for communities in hard to reach areas that may not have the funds to access leading virus detection equipment.

	Ebola-Neutralizing Antibodies The Ebola virus causes severe and often lethal infections. While an efficient treatment has not yet been found, it has been observed that Ebola-infection survivors develop antibodies against the virus, from which antibody-therapies could be derived. Recently, an international research collaboration has shown that in a safe, non-infectious vaccination trial, effective antibodies occurred soon after vaccination, raising the expectation that future antibody therapies can be sourced in a safe manner.

	HIV Suppression Using Adenovirus-Mediated Gene Therapy Research on therapies against the Human Immunodeficiency Virus (HIV) has repeatedly demonstrated the potential of broadly neutralizing antibodies (bn-Abs) as successful therapeutic agents. Injection of such antibodies leads to a decrease in viral concentrations in blood. However, repeated injections are necessary to prevent the recovery of the virus.