What is the Role of Vascular Endothelial Growth Factor?

What is the Role of Vascular Endothelial Growth Factor?

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By Dr. Maho Yokoyama, Ph.D.Reviewed by Dr. Tomislav Meštrović, MD, Ph.D.

Formation of new blood vessels can be divided into two processes – vasculogenesis and angiogenesis. Vasculogenesis represents the formation of new blood vessels from hemangioblasts during embryonic development, while angiogenesis is the formation of new capillary branches from established blood vessels.

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• What is Vascular Endothelial Growth Factor?
• How is VEGF production triggered?
• How does VEGF stimulate the growth of new blood vessels?
• What are the normal roles of VEGF?
• What roles does VEGF play in cancer?