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1. Tissue of origin dictates GOT1 dependence and confers synthetic lethality to radiotherapy

   Authors:Barbara S. Nelson, Lin Lin, Daniel M. Kremer, Cristovão M. Sousa, Cecilia Cotta-Ramusino, Amy Myers, Johanna Ramos, Tina Gao, Ilya Kovalenko, Kari Wilder-Romans, Joseph Dresser, Mary Davis, Ho-Joon Lee, Zeribe C. Nwosu, Scott Campit, Oksana Mashadova…

   Content type:Research

   2 January 2020

2. Cysteine catabolism and the serine biosynthesis pathway support pyruvate production during pyruvate kinase knockdown in pancreatic cancer cells

   Authors:Lei Yu, Shao Thing Teoh, Elliot Ensink, Martin P. Ogrodzinski, Che Yang, Ana I. Vazquez and Sophia Y. Lunt

   Content type:Research

   30 December 2019

3. A systematic flux analysis approach to identify metabolic vulnerabilities in human breast cancer cell lines

   Authors:Sheree D. Martin and Sean L. McGee

   Content type:Research

   27 December 2019

4. HIF1/2-exerted control over glycolytic gene expression is not functionally relevant for glycolysis in human leukemic stem/progenitor cells

   Authors:Albertus T. J. Wierenga, Alan Cunningham, Ayşegül Erdem, Nuria Vilaplana Lopera, Annet Z. Brouwers-Vos, Maurien Pruis, André B. Mulder, Ulrich L. Günther, Joost H. A. Martens, Edo Vellenga and Jan Jacob Schuringa

   Content type:Research

   27 December 2019

5. SGLT2 inhibition slows tumor growth in mice by reversing hyperinsulinemia

   Authors:Ali R. Nasiri, Marcos R. Rodrigues, Zongyu Li, Brooks P. Leitner and Rachel J. Perry

   Content type:Research

   11 December 2019