Can Bone Marrow Cells Stimulate Generation of New Neurons in Babies with CHD?

Can cells collected from bone marrow stimulate generation of new neurons in babies with CHD? The NIH has awarded Children’s National Hospital $2.5 million to test the hypothesis that mesenchymal stromal cells, collected from allogeneic bone marrow, may promote regeneration of damaged neuronal and glial cells in the early postnatal brain. The study is a single-center collaboration between three Children’s National physician-researchers: Richard Jonas, M.D., Catherine Bollard, M.B.Ch.B., M.D. and Nobuyuki Ishibashi, M.D. If successful, the trial will determine the safety of the proposed treatment in humans and set the stage for a Phase 2 efficacy trial of what could potentially be the first treatment for delays in brain development that happen before birth as a consequence of congenital heart disease.

BPA analogues may be less likely to disrupt heart rhythm Some chemical alternatives to plastic bisphenol-a (BPA), which is still commonly used in medical settings, may be less disruptive to heart electrical function than BPA. Virtual cardiology follow-ups may save families time and money A recent pilot study demonstrated that health provider follow-ups delivered via computer or smartphone are a feasible alternative to in-person patient follow-ups for some pediatric cardiac conditions. Children’s National partners with Sabará Hospital Infantil Through a new partnership with Sabará Hospital Infantil in São Paulo, Brazil, Children’s National Hospital will provide access to pediatric cardiac intensive care specialists and consultations via telehealth. This is the first international telehealth offering from Children’s National for pediatric cardiac critical care. Making healthcare innovation for children a priority Recently, Kurt Newman, M.D., president and CEO of Children’s National Hospital, authored an opinion piece for the popular political website, The Hill. In the article, he called upon stakeholders from across the landscape to address the significant innovation gap in children’s healthcare versus adults.

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