DNA hypermethylation of sirtuin 1 ( SIRT1 ) caused by betel quid chewing—a possible predictive biomarker for malignant transformation | Clinical Epigenetics | Full Text

DNA hypermethylation of sirtuin 1 ( SIRT1 ) caused by betel quid chewing—a possible predictive biomarker for malignant transformation | Clinical Epigenetics | Full Text

DNA hypermethylation of sirtuin 1 (SIRT1) caused by betel quid chewing—a possible predictive biomarker for malignant transformation

DNA hypermethylation of tumor suppressor genes is observed in precancerous lesions and oral cancer of individuals with the habits of betel quid (BQ) chewing. SIRT1 has been identified as playing a role in the mai...

Authors:Shajedul Islam, Osamu Uehara, Hirofumi Matsuoka, Yasuhiro Kuramitsu, Bhoj Raj Adhikari, Daichi Hiraki, Seiko Toraya, Asiri Jayawardena, Ichiro Saito, Malsantha Muthumala, Hiroki Nagayasu, Yoshihiro Abiko and Itsuo Chiba

Citation:Clinical Epigenetics 2020 12:12

Content type:Research

Published on: 13 January 2020

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