Nrf2 activation through the PI3K/GSK-3 axis protects neuronal cells from Aβ-mediated oxidative and metabolic damage | Alzheimer's Research & Therapy | Full Text

Nrf2 activation through the PI3K/GSK-3 axis protects neuronal cells from Aβ-mediated oxidative and metabolic damage | Alzheimer's Research & Therapy | Full Text

Nrf2 activation through the PI3K/GSK-3 axis protects neuronal cells from Aβ-mediated oxidative and metabolic damage

Mounting evidence points to a crucial role of amyloid-β (Aβ) in the pathophysiology of Alzheimer’s disease (AD), a disorder in which brain glucose hypometabolism, downregulation of central elements of phosphor...

Authors:Krystal Sotolongo, Jorge Ghiso and Agueda Rostagno

Citation:Alzheimer's Research & Therapy 2020 12:13

Content type:Research

Published on: 13 January 2020

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