sábado, 10 de octubre de 2020

Roche Acquires TMEM16A Portfolio for Cystic Fibrosis Treatment

Roche Acquires TMEM16A Portfolio for Cystic Fibrosis Treatment


Cystic Fibrosis Weekly Update

Contents:

Roche Acquires TMEM16A Portfolio for CF Treatment

Oct 09, 2020 07:00 am | Sara Guariglia



TMEM16ARoche has acquired Enterprise Therapeutics’s TMEM16A potentiator portfolio, which includes ETD002, a therapeutic candidate being evaluated in Phase 1 clinical trials for the treatment of cystic fibrosis (CF). The TMEM16A portfolio is focused on treatments for CF and other severe respiratory disorders characterized by excessive mucus congestion. Genentech, a member of the Roche Group, now […]

The post Roche Acquires TMEM16A Portfolio for CF Treatment appeared first on Cystic Fibrosis News Today.
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Tobacco Smoke Exposure Limits Symdeko Benefit in Pediatric CF Patients

Oct 08, 2020 07:00 am | Forest Ray



Symdeko, tobacco smoke exposureExposure to tobacco smoke limits the medicinal benefit of Symdeko (tezacaftor/ivacaftor combo) in young patients with cystic fibrosis (CF), according to a recent study. This finding suggests that smoking must be avoided for Symdeko to provide its full benefits. It also suggests that the effects of smoke exposure on next-generation cystic fibrosis transmembrane receptor (CFTR) […]

The post Tobacco Smoke Exposure Limits Symdeko Benefit in Pediatric CF Patients appeared first on Cystic Fibrosis News Today.
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