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Genomics|Features|Suicide

Suicide

Suicide: Recent Genomic Insights - March 2, 2015

Genome-wide association studies of suicidal behaviors: a review.
Sokolowski Marcus et al. Eur Neuropsychopharmacol2014 Oct (10) 1567-77

Two novel genomic rearrangements identified in suicide subjects using a-CGH array.
Lombardo Barbara et al. Clin. Chem. Lab. Med. 2015 Feb 13.

Investigating the role of early childhood abuse and HPA axis genes in suicide attempters with bipolar disorder.
Breen Marie E et al. Psychiatr. Genet. 2015 Feb 24.

Molecular convergence of neurodevelopmental disorders.
Chen Elizabeth S et al. Am. J. Hum. Genet. 2014 Nov 6. (5) 490-508

Genetic relationships between suicide attempts, suicidal ideation and major psychiatric disorders: a genome-wide association and polygenic scoring study.
Mullins Niamh et al. Am. J. Med. Genet. B Neuropsychiatr. Genet. 2014 Jul (5) 428-37

Genome-wide methylomic analysis of monozygotic twins discordant for adolescent depression.
Dempster Emma L et al. Biol. Psychiatry 2014 Dec 15. (12) 977-83

A unique gene expression signature associated with serotonin 2C receptor RNA editing in the prefrontal cortex and altered in suicide.
Di Narzo Antonio Fabio et al. Hum. Mol. Genet. 2014 Sep 15. (18) 4801-13

Association study of GABRG2 polymorphisms with suicidal behaviour in schizophrenia patients with alcohol use disorder.
Zai Clement C et al. Neuropsychobiology 2014 (3) 154-8

Epigenetic studies of suicidal behavior.
Bani-Fatemi Ali et al. Neurocase 2015 (2) 134-43

Suicide Prevention: Family History & Genomics - September 18, 2014

CDC information: Suicide can be prevented. Each year, more than 39,000 Americans take their own lives and about 487,000 people receive medical care for self-inflicted injuries

New CDC blog post: Suicide, family history, and genomics

CDC information: Risk factors for suicide include family history of suicide and family history of child maltreatment

National Institute for Mental Health information: Suicide prevention

Did you know?>200 genes have been reported in relation to suicide risk, including 10 genomewide association studies? To find out more, visit the HuGE Navigator

Check out genetic conditions and tests associated with suicide, from the NIH Genetic Testing Registry

Could a genetic test predict the risk for suicide? Scientists are hunting for the genetic basis of suicide and developing suicide DNA tests, by Antonio Regalado, MIT Technology Review, Aug 13

Blood test that allegedly predicts suicide risk only looks promising in the media, not in science, by Cecile Janssens, Huffington Post, Aug 19

Team approach helps teen depression, by Dr. Francis Collins, NIH Director, Sep 9