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Genomics|Features|Lynch Syndrome

Lynch Syndrome

March is Colorectal Cancer Awareness Month - March 5, 2015

CDC information: Colorectal Cancer Awareness

Screen for Life: National Colorectal Cancer Action Campaign

CDC genomics and health information: Colorectal Cancer Awareness

CDC information: Genetic testing for hereditary colorectal cancer

Listen to a CDC podcast about genetic testing for Lynch syndrome

Lynch Syndrome: Basics, Outcomes and Insights - February 23, 2015

A modified Lynch syndrome screening algorithm in colon cancer: BRAF immunohistochemistry is efficacious and cost beneficial.
Roth Rachel M et al. Am. J. Clin. Pathol. 2015 Mar (3) 336-43

Clinicopathologic analysis with immunohistochemistry for DNA mismatch repair protein expression in synchronous primary endometrial and ovarian cancers.
Kobayashi Yusuke et al. Int. J. Gynecol. Cancer 2015 Mar (3) 440-6

Improving the uptake of predictive testing and colorectal screening in Lynch syndrome: a regional primary care survey.
Barrow P et al. Clin. Genet. 2015 Feb 4.

Milestones of Lynch syndrome: 1895-2015.
Lynch Henry T et al. Nat. Rev. Cancer 2015 Feb 12.

Lynch syndrome: The basics, by Dennis Ahnen, Fight Colorectal Cancer Blog Post, Jan 15

Economic evaluation of genetic screening for Lynch syndrome in Germany.
Franziska Severin, et al. Genetics in Medicine, January 8, 2015

Barriers and motivators for referral of patients with suspected Lynch syndrome to cancer genetic services: A qualitative study
Tan YY & Fitzgerald LJ J Pers Med 2014;4(1):20-34

Next-generation strategies for hereditary colorectal cancer risk assessment.
Yurgelun MB J Clin Oncol. 2015 Jan 5. pii: JCO.2014.58.9895.

Screening for Lynch syndrome: It is time to shift the focus
Kidambi TD & Terdiman JP Dig Dis Sci 2015 Jan

Cost-effectiveness and diagnostic effectiveness analyses of multiple algorithms for the diagnosis of Lynch syndrome. 
Gould-Suarez M, et al. Dig Dis Sci 2014 Dec;59(12)2913-26.

Lynch Syndrome: Recent Insights - November 6, 2014

Applying public health screening criteria: How does universal newborn screening compare to universal tumor screening for Lynch syndrome in adults with colorectal cancer?
Cragun D, et al. J Genet Couns. 2014 Oct 18

Is it all Lynch syndrome?: An assessment of family history in individuals with mismatch repair–deficient tumors.
Katherine M. Dempsey et al. Genetics in Medicine, October 23, 2014  

Long-term psychosocial and behavioral adjustment in individuals receiving genetic test results in Lynch syndrome.
Esplen M, et al. Clin Genet. 2014 Oct 9.

Colonoscopy in patients with Lynch syndrome: no room for error.
Kravochuck SE, Church JM. ANZ J Surg. 2014 Oct 29

Identifying Persons with Lynch Syndrome: Why and How?
Ladabaum U. Dig Dis Sci. 2014 Oct 26.

The impact of risk-reducing gynaecological surgery in premenopausal women at high risk of endometrial and ovarian cancer due to Lynch syndrome.
Moldovan R, Keating S, Clancy T. Fam Cancer. 2014 Oct 24.

Long-term psychosocial and behavioral adjustment in individuals receiving genetic test results in Lynch syndrome.
Esplen MJ, et al. Clin Genet. 2014 Oct 9.

Lynch Syndrome: Awareness and Implementation - September 25, 2014

CDC information: Genetic testing for hereditary colorectal cancer

CDC public health genomics implementation tool kit for health departments- check out Lynch syndrome section

Genetic testing of tumor is recommended for colorectal cancer patients, Science Daily Aug 5

Guidelines on genetic evaluation and management of Lynch syndrome: A consensus statement by the US Multi-Society Task Force on Colorectal Cancer.
Giardiello FM et al. Dis Colon Rectum. 2014 Aug;57(8):1025-48

NCCN updates guidelines for hereditary colon cancer testing, (March, 2014)

CDC podcast: Genetic testing for Lynch Syndrome in colorectal cancer

Colonoscopy screening compliance and outcomes in patients with Lynch Syndrome.
Newton K et al.  Colorectal Dis. 2014 Sep 11

Lynch Syndrome - GeneReviews® - NCBI Bookshelf by W Kohlmann et al. (2012)

Lynch syndrome: a pediatric perspective.
SC Huang  et al. J Pediatr Gastroenterol Nutr. 2014

Lynch Syndrome Screening Network- Vision is to reduce the cancer burden associated with Lynch syndrome

Lynch Syndrome International: Mission is to provide support for individuals afflicted with Lynch syndrome, create public awareness of the syndrome, and educate the general public and health care professionals