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Genomics|Features|Infectious Diseases

Pathogen Genomics

Pathogen Genomics: From Research to Implementation - September 24, 2015

CDC and Related Info

• Infectious diseases: Precision medicine for public health
• CDC Advanced Molecular Detection Accomplishments 2014
• Advanced Molecular Detection Initiative
• CDC and partners investigate newly discovered virus
• Pathogen Genomics

New CDC Blog Post:Infectious diseases: Precision medicine for public health

How next-generation sequencing and multiscale data analysis will transform infectious disease management.
Pak T et al. Clin. Infect. Dis. 2015 Aug

Real-time digital pathogen surveillance — the time is now
Gardy J et al. Genome Biology, July 30, 2015

Genomic technologies speed pathogen detection 
Stephenson J , JAMA, July 21, 2015

Pathogen genomics into practice
Luheshi L, et al. PHG Foundation 2015 July 8

An integrated strategy for implementing infectious disease genomics, by Laura Blackburn, PHG Foundation, Jul 9

Pathogen genomics into practice: from potential to reality, by Sobia Raza, PHG Foundation, Jul 9

What was old is new again: using the host response to diagnose infectious disease.
Ko ER et al. Expert Rev. Mol. Diagn. 2015 Jul 4. 1-16

The role of pathogen genomics in assessing disease transmission.
Sintchenko V et al. BMJ 2015 h1314

A microbiological revolution meets an ancient disease: improving the management of tuberculosis with genomics.
Wlodarska M et al. Clin. Microbiol. Rev. 2015 Apr (2) 523-39

The application of genomics to tracing bacterial pathogen transmission.
Croucher NJ et al. Curr. Opin. Microbiol. 2015 Feb 62-7

Molecular epidemiology and genomics of group A Streptococcus.
Bessen DE et al. Infect. Genet. Evol. 2015 Jul 393-418

Epidemiologic data and pathogen genome sequences: a powerful synergy for public health.
Grad YH et al. Genome Biol. 2014 (11) 538

Advanced Molecular Detection and Public Health - April 14, 2015

CDC Advanced Molecular Detection Accomplishments 2014

CDC names winner of the “No-Petri-Dish” diagnostic test challenge

CDC Advanced Molecular Detection Initiative

Genomics and Infectious Disease Weekly Update features emerging role of pathogen genomics in infectious disease control and prevention

Genomics of Infectious Diseases: Progress and Challenges - November 26, 2014

Genome Medicine: Genomics of infectious diseases special issue, Nov 2014

Editorials:

Next-generation pathogen genomics
Weinstock GM, Peacock SJ. Genome Biology 2014, 15:528.

Microbial sequencing to improve individual and population health
Peacock SJ, Weinstock CM. Genome Medicine 2014, 6:103.

Stopping outbreaks with real-time genomic epidemiology
Tang P, Gardy JL. Genome Medicine 2014, 6:104.

Epidemiologic data and pathogen genome sequences: a powerful synergy for public health
Grad Y, Lipsitch M. Genome Biology 2014, 15:538.

Genomic analysis of emerging pathogens: methods, application and future trends
Lucy M Li, et al. Genome Biology, November 2014 

Enhanced methods for unbiased deep sequencing of Lassa and Ebola RNA viruses in clinical and biological samples
Christian B Matranga et al. Genome Biology, November 2014

Translating genomics research into control of tuberculosis: lessons learned and future prospects
Warner DF, Mizrahi V. Genome Biology 2014, 15:514.

Empowering African genomics for infectious disease control
Folarin OA, et al. Genome Biology 2014, 15:515.

Genomics and infectious disease: a call to identify the ethical, legal and social implications for public health and clinical practice
Geller G, et al. Genome Medicine 2014, 6:106. 

Pathogen Genome Sequencing: Public Health Applications - October 22, 2014

CDC Advanced Molecular Detection Initiative: Imagine doing a 10,000-piece jigsaw puzzle in the time it takes to finish a 100-piece puzzle. Apply that to infectious disease control, and that’s AMD at work. Now imagine putting together that 10,000-piece puzzle when key pieces are missing, disease is spreading, and people are dying. AMD gives CDC scientists the “key pieces” they need to protect people from ever-changing infectious disease threats

Genomic polish for shoe-leather epidemiology
Steven Y. C. Tong. Nature Reviews Microbiology 11, 8 (2013)

In Snow's footsteps: Commentary on shoe-leather and applied epidemiology 
Denise Koo and Stephen B. Thacker. Epidemiologic Reviews (2010)

Sherlock genomes — viral investigator
Sarah E. Smith & Rachael S. Wash Nature Reviews Microbiology 11, 150 (2013)

High-throughput bacterial genome sequencing: an embarrassment of choice, a world of opportunity. 
Nature Reviews Microbiology10, 599-606 (2012)

Transforming clinical microbiology with bacterial genome sequencing
Nature Reviews Genetics13, 601-612 (2012)

Bacterial genome sequencing in the clinic: bioinformatic challenges and solutions
W. Florian Fricke & David A. Rasko. Nature Reviews Genetics 15, 49-55 (2014)

Pathogen Genomics: Utility in Healthcare and Public Health - June 5, 2014

ePathGen - a new e-learning package in pathogen genomics
Eurosurveillance, Volume 19, Issue 21, 29 May 2014

CDC information: Multistate outbreak of Shiga toxin-producing Escherichia coli O157:H7 infections

CDC information: Pathogen genomics has changed the landscape of the fight against infectious diseases

CDC Advanced Molecular Detection Initiative

FDA Consumer Information: Whole Genome Sequencing Helps Identify Dangerous Bacteria

Whole genome sequencing helps FDA identify dangerous bacteria, FDA

GenomeTrakr helps FDA identify dangerous bacteria, Health News Digest, Jun 2

Beating the bugs: The pathogen genomics revolution, Leila Lehushi, PHG Foundation, May 2014  

Health care: Bring microbial sequencing to hospitals, Sharon Peacock Nature News, May 22