AIDSinfo Releases Brief Versions of the HIV/AIDS Medical Practice Guidelines

News and Features AIDSinfo Releases Brief Versions of the HIV/AIDS Medical Practice Guidelines AIDSinfo is pleased to announce the release of brief versions of the federally approved HIV/AIDS medical practice guidelines. Health care providers have requested shorter versions of the guidelines that are easier to use at the point of care, and AIDSinfo used this feedback to produce brief versions of the following guidelines: Adult and Adolescent Antiretroviral (ARV) Guidelines (recently updated on October 25, 2018) Adult and Adolescent Opportunistic Infections (OI) Guidelines Perinatal ARV Guidelines Pediatric ARV Guidelines Pediatric OI Guidelines The brief versions contain only the Panel’s recommendations and tables, allowing health care providers to quickly locate relevant information when caring for people with HIV. They are easily accessed by selecting the Brief Guidelines tab at the top of each guideline section. AIDSinfo welcomes your feedback on the brief guidelines. Please email your comments or questions to ContactUs@aidsinfo.nih.gov. Adult and Adolescent Opportunistic Infections Guidelines Updated The following sections of the Guidelines for the Prevention and Treatment of Opportunistic Infections in HIV-Infected Adults and Adolescents were updated on November 13, 2018: Hepatitis B Virus Infection: The panel added information regarding the recently approved two-dose hepatitis B vaccine conjugated to a TLR9 agonist (Heplisav-B). Since there are no data on this vaccine in HIV-infected individuals, the panel presents it as an option with a CIII recommendation. The panel added recommendations regarding considerations to prevent HBV reactivation during immunosuppressive therapy in patients with HBsAg-negative/anti-HBc positive disease, which include starting tenofovir/emtricitabine backbone when possible with other options presented if this cannot be given. Progressive Multifocal Leukoencephalopathy/JC Virus Infection: The section was updated to reflect current information about the value of plasma PCR and to include updated references on failed therapies.