Cystic Fibrosis Weekly Update

Contents:

Decreasing Acidity of Airway Liquid in Newborn CF Patients May Reduce Infection Risk, Study Suggests

May 01, 2019 07:00 am | Alejandra Viviescas

Normalizing the acidity in the thin layer of liquid covering the airways of newborns with cystic fibrosis might make them more resistant to bacterial infections, a study has found. The study’s researchers also identified two proteins, pendrin and ATP12A, that could be targeted to regulate acidity levels of the airway liquid in these infants, which is “significantly” more acidic […]
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Here’s What It Feels Like to Have Cystic Fibrosis

Apr 30, 2019 09:00 am | Brad Dell

There’s a rattle in my chest when I inhale. I sweat and dig my nails into my palm. I feel it, microseconds of dread and fear as the rattling gives way to something like the plugging and unplugging of suction cups in my airways. That quickly escalates into a “cough attack.” I cough, cough, cough, […]
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CF-associated Bacteria and Fungi Affect Each Other’s Growth, According to In Vitro Study

Apr 30, 2019 07:30 am | Santiago Gisler

Pseudomonas aeruginosa and Scedosporium fungi, CF

Physical and signaling interactions between two pathogen groups that often affect patients with cystic fibrosis (CF) — Pseudomonas aeruginosa bacteria and Scedosporium fungi — result in a growth effect (inhibition or enhancement) of these microorganisms, according to an in vitro study. CF therapies such as antibiotics or corticosteroids also affected the growth of the fungi, the researchers found, highlighting the importance of a […]
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