Dr. Shizhao Li, Dr. Yuanyuan (Rose) Li & Dr. Trygve Tollefsbol
Dr. Shizhao Li is a Postdoctoral Fellow in the Department of Biology at UAB. He acquired his Ph.D. degree in Animal Nutrition and Nutri-epigenetics from the Northwest A&F University in 2017. Dr. Li has been developing a unique view of epigenome dynamic in early stage of ontogeny and his research now primarily focuses on early life consumption of combined botanicals to neutralize epigenomic dysregulation in cancers utilizing transgenic mouse models.
Dr. Yuanyuan (Rose) Li is an Assistant Professor in the Department of Pharmacology and Toxicology at UAB. She received her Ph.D. degree in Oncology from the Chinese Academy of Medical Sciences and Peking Union Medical College, China, in 2006. Dr. Li’s research has primarily focused on studying the interaction of epigenetic mechanisms and environmental factors such as bioactive dietary compounds in human diseases including cancer, obesity and aging utilizing transgenic mice as main animal models.
Dr. Trygve Tollefsbol is a Professor of Biology and a Senior Scientist in the Comprehensive Cancer Center, the Comprehensive Center for Healthy Aging, the Comprehensive Diabetes Center and the Nutrition Obesity Research Center at the University of Alabama at Birmingham. He received doctorate degrees in molecular biology and osteopathic medicine at the University of North Texas Health Sciences Center and trained at Duke University and the University of North Carolina. His research focuses on the epigenetics of cancer prevention and aging.
Dr. Yuanyuan (Rose) Li is an Assistant Professor in the Department of Pharmacology and Toxicology at UAB. She received her Ph.D. degree in Oncology from the Chinese Academy of Medical Sciences and Peking Union Medical College, China, in 2006. Dr. Li’s research has primarily focused on studying the interaction of epigenetic mechanisms and environmental factors such as bioactive dietary compounds in human diseases including cancer, obesity and aging utilizing transgenic mice as main animal models.
Dr. Trygve Tollefsbol is a Professor of Biology and a Senior Scientist in the Comprehensive Cancer Center, the Comprehensive Center for Healthy Aging, the Comprehensive Diabetes Center and the Nutrition Obesity Research Center at the University of Alabama at Birmingham. He received doctorate degrees in molecular biology and osteopathic medicine at the University of North Texas Health Sciences Center and trained at Duke University and the University of North Carolina. His research focuses on the epigenetics of cancer prevention and aging.
The epigenetics diet: A barrier against environmental pollution
Early-life nutrition can profoundly affect development through the regulation of gene expression even when the DNA is not altered. In this blog, a research team out of University of Alabama at Birmingham summarize the evidence that an “epigenetics diet” can help protect against adverse effects of environmental pollution exposure whilst in utero and after birth.
Early-life dietary nutrition can profoundly affect individual developmental fate and disease prevention. For example, the presence of absence of royal jelly determines whether the larvae of female honey bees develop into a queen (presence of jelly) or a sterile worker (absence of jelly). In a recent review article published in Clinical Epigenetics, we have reported important roles of specific diets in protection of environmental pollution-induced genetic/epigenetic disorders through the regulation of gene expression even when the DNA is not altered.
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