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Clinical Epigenetics

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1. Content Type:Research

     |  24 July 2019

   A prognostic CpG score derived from epigenome-wide profiling of tumor tissue was independently associated with colorectal cancer survival

   Authors:Min Jia, Yan Zhang, Lina Jansen, Viola Walter, Dominic Edelmann, Melanie Gündert, Katrin E. Tagscherer, Wilfried Roth, Melanie Bewerunge-Hudler, Esther Herpel, Matthias Kloor, Alexis Ulrich, Barbara Burwinkel, Hendrik Bläker, Jenny Chang-Claude, Hermann Brenner…
2. Content Type:Short Report

     |  23 July 2019

   Whole-genome DNA hyper-methylation in iPSC-derived dopaminergic neurons from Parkinson’s disease patients

   Authors:Rubén Fernández-Santiago, Angelika Merkel, Giancarlo Castellano, Simon Heath, Ángel Raya, Eduard Tolosa, María-José Martí, Antonella Consiglio and Mario Ezquerra
3. Content Type:Research

     |  23 July 2019

   Suv39h1 promotes facet joint chondrocyte proliferation by targeting miR-15a/Bcl2 in idiopathic scoliosis patients

   Authors:Jiong Li, Guanteng Yang, Shaohua Liu, Longjie Wang, Zhuotao Liang and Hongqi Zhang
4. Content Type:Research

     |  22 July 2019

   Genomic and epigenomic predictors of response to guadecitabine in relapsed/refractory acute myelogenous leukemia

   Authors:Woonbok Chung, Andrew D. Kelly, Patricia Kropf, Henry Fung, Jaroslav Jelinek, Xiang Yao Su, Gail J. Roboz, Hagop M. Kantarjian, Mohammad Azab and Jean-Pierre J. Issa
5. Content Type:Research

     |  22 July 2019

   A combined epigenome- and transcriptome-wide association study of the oral masticatory mucosa assigns CYP1B1 a central role for epithelial health in smokers

   Authors:Gesa M. Richter, Jochen Kruppa, Matthias Munz, Ricarda Wiehe, Robert Häsler, Andre Franke, Orlando Martins, Yvonne Jockel-Schneider, Corinna Bruckmann, Henrik Dommisch and Arne S. Schaefer