Transforming Adversity into Progress
Jul 15, 2019 09:00 am | Tré LaRosa
In my senior year of high school, I went to the exercise section of Dick’s Sporting Goods and searched for boxing gloves. I had decided on a whim that I wanted to learn how to box. At the time, I was mostly weight lifting, and the majority of my cardio was playing sports with my […]
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Babies Treated with Synagis Show No Lasting Benefits in Lung Health as 7-Year-Olds, Real-world Study Finds
Jul 15, 2019 07:00 am | Alice Melão
Treating infants with cystic fibrosis (CF) with the antiviral therapy Synagis (palivizumab) does not improve long-term outcomes in lung health, real-world data show. Routine use of Synagis is not recommended by the American Academy of Pediatrics for babies with CF, although its use can be considered in those at risk of chronic lung disease. These findings suggest […]
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Different CFTR Potentiators Bind to Same Flexible Spot on Protein, Study Finds
Jul 12, 2019 07:00 am | Jose Marques Lopes, PhD
Approved and investigative cystic fibrosis (CF) treatments known as CFTR potentiators work by binding to the same flexible protein spot — a place that acts like a hinge — and keeping it open, according to a study whose findings may lead to more effective therapies. The research, “Structural identification of a hotspot on CFTR for potentiation,” was published […]
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What Does It Mean to Be a Patient?
Jul 11, 2019 09:00 am | Elly Aylwin-Foster
I have a funny relationship with the P-word. It feels as familiar as my own skin, yet somehow still alien. At clinics when I was growing up, I used to strain my eyes across the table, trying to read my doctors’ notes as they sat open in their files. Sometimes, I’d see my own name […]
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Eluforsen Improves CFTR Function in Cellular and Animal Models of CF, Study Says
Jul 11, 2019 07:00 am | Joana Carvalho
Eluforsen, an investigational therapy for the treatment of cystic fibrosis (CF), improves the function of the cystic fibrosis transmembrane conductance regulator (CFTR) protein in cellular and mice models of CF that carry the most common mutation associated with the disorder, a study says. The findings of the study, “Evaluation of eluforsen, a novel RNA oligonucleotide […]
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