jueves, 3 de octubre de 2019

Drug Discovery and Production | Medical News | Medical Articles | Drug Discovery and Production |

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 October 3, 2019 
 Drug Discovery and Production 
 The latest drug discovery news from News Medical 
 #ALT#Thermal Analysis Assures the Quality of Pharmaceuticals

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  KeysightTocriscreenTM Epigenetics Library
 
Tocriscreen Epigenetics Library includes the latest bioactive compounds against >40 epigenetic targets including epigenetics readers, writers, erasers and transcription modulators, and includes the latest bioactive compounds. Compound libraries can be used for target validation, drug repurposing and phenotypic screening.
 
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  KeysightHow to Monitor Phase Transitions in Pharmaceuticals
 
Polymorphism in pharmaceutical solids is the ability of a substance to exist in more than one molecular arrangement, resulting in numerous polymorphic forms which differ in their physiochemical properties such as solubility, melting point, stability, etc. It has a big impact on both the performance and processing of solid pharmaceutical products.
 
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 New antibiotics on the horizon as scientists discover a weakness in the cell wall of pathogenic bacteria
 
New antibiotics on the horizon as scientists discover a weakness in the cell wall of pathogenic bacteriaResearchers have discovered a weak spot in the cell wall of pathogenic bacteria that could lead to the development of new antibiotics. This was a joint collaboration between researchers at the Hokkaido University of Japan, Duke University in the US and The Catholic University of Korea.
 
 
 New mechanism that controls DNA repair identified
 
New mechanism that controls DNA repair identifiedDeoxyribonucleic acid (DNA), is the macromolecule that holds all hereditary and genetic information. Continuously under assault, alterations and damage to DNA can lead to many different health issues, including cancer. DNA is highly regulated within cells, where multiple mechanisms are at play to repair and protect its integrity. Scientists are still investigating these mechanisms to fully comprehend how these DNA repair processes are managed.
 
 
 Importance of Solubility and Lipophilicity in Drug Development
 
Importance of Solubility and Lipophilicity in Drug DevelopmentSolubility and lipophilicity are basic physicochemical properties, but also key parameters that can dictate the success or failure rate of drug discovery and development. In short, their measurement is pivotal for both in vitro and in silico evaluation of drug properties.
 
 
 Using AI to transform drug discovery in a big way
 
Using AI to transform drug discovery in a big wayAccording to the National Cancer Institute, approximately 38 percent of men and women will be diagnosed with cancer at some point in their lives. The current process for drug discovery is slow and sequential, and often involves high failure rates for drug candidates. Can artificial intelligence (AI) be used to transform the existing drug discovery process into a rapid, integrated, and patient-centric model?
 
 
 Exploring the Structure-Activity Relationship (SAR) of Drugs
 
Exploring the Structure-Activity Relationship (SAR) of DrugsThe structure-activity relationship (SAR) aids in understanding various aspects of drug discovery, from screening drug candidates to optimizing their properties. The effective biological activity is contributed by the various geometric and electrostatic interactions.
 
 
 'A new era of drug discovery’: Company develops drug using AI
 
'A new era of drug discovery’: Company develops drug using AIFor the first time, a Toronto-based company called Deep Genomics has discovered a drug target and corresponding candidate using artificial intelligence (AI). The company announced yesterday that its AI-based drug discovery platform has identified a new treatment target and drug candidate for Wilson disease, a potentially life-threatening genetic disorder.
 
 
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