Extracellular vesicles and regenerative medicine

Extracellular vesicles and regenerative medicine

Edited by Jeffrey Karp, Armand Keating and Kelvin Ng

An article collection in Stem Cell Research & Therapy.

Evidence implicating extracellular vesicles (EVs) in regenerative processes is rapidly accumulating. This series reviews recent progress in understanding EV biology and how it may be harnessed for therapy.

This series of articles has not been sponsored. All articles have undergone the journal’s standard peer review process overseen by the Series Editors, with final decisions made by the Editors-in-Chief. The Series Editors and Editors-in-Chief declare no competing interests.

View all collections published in Stem Cell Research & Therapy

1. Content type:Research

   BM-MSC-derived exosomes alleviate radiation-induced bone loss by restoring the function of recipient BM-MSCs and activating Wnt/β-catenin signaling

   Radiotherapy to cancer patients is inevitably accompanied by normal tissue injury, and the bone is one of the most commonly damaged tissues. Damage to bone marrow mesenchymal stem cells (BM-MSCs) induced by ra...

   Authors:Rui Zuo, Minghan Liu, Yanqiu Wang, Jie Li, Wenkai Wang, Junlong Wu, Chao Sun, Bin Li, Ziwen Wang, Weiren Lan, Chao Zhang, Chunmeng Shi and Yue Zhou

   Citation:Stem Cell Research & Therapy 2019 10:30

   Published on: 15 January 2019

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2. Content type:Research

   Early gestational mesenchymal stem cell secretome attenuates experimental bronchopulmonary dysplasia in part via exosome-associated factor TSG-6

   Mesenchymal stem cells (MSCs) are promising tools for the treatment of human lung disease and other pathologies relevant to newborn medicine. Recent studies have established MSC exosomes (EXO), as one of the m...

   Authors:Sushma Chaubey, Sam Thueson, Devasena Ponnalagu, Mohammad Afaque Alam, Ciprian P. Gheorghe, Zubair Aghai, Harpreet Singh and Vineet Bhandari

   Citation:Stem Cell Research & Therapy 2018 9:173

   Published on: 26 June 2018

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3. Content type:Review

   Illuminating the physiology of extracellular vesicles

   Extracellular vesicles play a crucial role in intercellular communication by transmitting biological materials from donor cells to recipient cells. They have pathophysiologic roles in cancer metastasis, neurod...

   Authors:Hongyoon Choi and Dong Soo Lee

   Citation:Stem Cell Research & Therapy 2016 7:55

   Published on: 16 April 2016

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4. Content type:Review

   Extracellular vesicles derived from mesenchymal stromal cells: a therapeutic option in respiratory diseases?

   Extracellular vesicles (EVs) are plasma membrane-bound fragments released from several cell types, including mesenchymal stromal cells (MSCs), constitutively or under stimulation. EVs derived from MSCs and oth...

   Authors:Soraia C. Abreu, Daniel J. Weiss and Patricia R. M. Rocco

   Citation:Stem Cell Research & Therapy 2016 7:53

   Published on: 14 April 2016

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5. Content type:Review

   Acellular approaches for regenerative medicine: on the verge of clinical trials with extracellular membrane vesicles?

   Extracellular vesicles (EVs) are a heterogeneous population of naturally occurring secreted small vesicles, with distinct biophysical properties and different functions both in physiology and under pathologica...

   Authors:Almudena Fuster-Matanzo, Florian Gessler, Tommaso Leonardi, Nunzio Iraci and Stefano Pluchino

   Citation:Stem Cell Research & Therapy 2015 6:227

   Published on: 2 December 2015

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6. Content type:Review

   Molecular signatures of mesenchymal stem cell-derived extracellular vesicle-mediated tissue repair

   Extracellular vesicles (EVs) play important roles in intercellular communications via their content molecules, and mimic, at least in part, the roles that are played by their originating cells. Consistent with...

   Authors:Takeshi Katsuda and Takahiro Ochiya

   Citation:Stem Cell Research & Therapy 2015 6:212

   Published on: 11 November 2015

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7. Content type:Review

   Role of extracellular RNA-carrying vesicles in cell differentiation and reprogramming

   Growing evidence suggests that transcriptional regulators and secreted RNA molecules encapsulated within membrane vesicles modify the phenotype of target cells. Membrane vesicles, actively released by cells, r...

   Authors:Peter J. Quesenberry, Jason Aliotta, Maria Chiara Deregibus and Giovanni Camussi

   Citation:Stem Cell Research & Therapy 2015 6:153

   Published on: 3 September 2015

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