martes, 20 de noviembre de 2018

Genetics - Nov 20, 2018 Edition | Medical News | Medical Articles

Medical News | Medical Articles



 
 November 20, 2018 
 Genetics 
 The latest Genetics news from News Medical 
 About 300 million bits of DNA are missing from basic reference genome, report scientistsAbout 300 million bits of DNA are missing from basic reference genome, report scientists
 
For the past 17 years, most scientists around the globe have been using the nucleic acid sequence, or genome, an assembly of DNA information, from primarily a single individual as a kind of "baseline" reference and human species representation for comparing genetic variety among groups of people.
 
 
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   Non-coding genetic variant plays key role in endothelial function and disease incidenceNon-coding genetic variant plays key role in endothelial function and disease incidence
 
Atherosclerotic disease, the slow and silent hardening and narrowing of the arteries, is a leading cause of mortality worldwide. It is responsible for more than 15 million deaths each year, including an estimated 610,000 people in the United States.
 
 Personalized scheduling of radiotherapy using genetic data could reduce side effects
 
Personalized scheduling of radiotherapy using genetic data could reduce side effectsA new clinical study led by the University of Leicester and conducted in the HOPE clinical trials facility at Leicester's Hospitals has revealed the pivotal role that changing the time of day that a patient receives radiotherapy could play in altering radiotherapy toxicity.
 
 
 Researchers identify genetic changes that could increase risk for death by suicide
 
Researchers identify genetic changes that could increase risk for death by suicideResearchers at University of Utah Health identified four gene changes that occur more frequently in people who died by suicide that may point to increased risk in vulnerable individuals.
 
 
 Participation project calls for relaxing research ban on germline interventions
 
Participation project calls for relaxing research ban on germline interventionsAre genetic defects allowed to be repaired by intervening with sperm or egg cells, or even human embryos? Thanks to genetic scissors such as CRISPR/Cas, such interventions in the germline could soon become a medical reality.
 
 
 Obesity significantly increases risk of Type 2 diabetes and coronary artery disease
 
Obesity significantly increases risk of Type 2 diabetes and coronary artery diseaseA Cleveland Clinic genetic analysis has found that obesity itself, not just the adverse health effects associated with it, significantly increases the risk of Type 2 diabetes and coronary artery disease. The paper was published today in the Journal of the American Medical Association Network Open.
 
 
 Gene editing could be used to halt kidney disease in patients with Joubert syndrome
 
Gene editing could be used to halt kidney disease in patients with Joubert syndromeFor the first time scientists have identified how to halt kidney disease in a life-limiting genetic condition, which may pave the way for personalized treatment in the future.
 
 
 Scientists use cryo-EM to capture freeze-frames of molecule’s 'lock-and-load' on DNA
 
Scientists use cryo-EM to capture freeze-frames of molecule’s 'lock-and-load' on DNAPushing the limits of cryo-electron microscopy, University of California, Berkeley, scientists have captured freeze-frames of the changing shape of a huge molecule, one of the body's key molecular machines, as it locks onto DNA and loads the machinery for reading the genetic code.
 

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