The dysregulation of tRNAs and tRNA derivatives in cancer | Journal of Experimental & Clinical Cancer Research | Full Text

The dysregulation of tRNAs and tRNA derivatives in cancer | Journal of Experimental & Clinical Cancer Research | Full Text

Featured Article: The dysregulation of tRNAs and tRNA derivatives in cancer

Transfer RNAs (tRNAs) are traditionally considered to participate in protein translation. Recent studies show that dysregulation has been observed in both tRNAs and tRNA derivatives generated by the specific cleavage of pre- and mature tRNAs in the progression of cancer. Shi-qiong Huang, et al. review the importance of the dysregulation of tRNAs and tRNA derivatives during the development of different types of cancers, aiming at a better understanding of the tumorigenesis and providing new ideas for the treatment of these cancers.

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