Children’s Environmental Health
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Association of low-level blood lead with serum uric acid in U.S. adolescents: a cross-sectional study
Uncertainty remains regarding the association between blood lead levels (BLL) and serum uric acid (SUA) with relatively low BLL exposure because of limited data in the adolescent population. We examined the as...Environmental Health 2019 18:86Published on: 16 October 2019
Prenatal maternal and childhood bisphenol a exposure and brain structure and behavior of young children
Bisphenol A (BPA) is commonly used in the manufacture of plastics and epoxy resins. In North America, over 90% of the population has detectable levels of urinary BPA. Human epidemiological studies have reporte...Environmental Health 2019 18:85Published on: 15 October 2019Ambient air pollution is associated with pediatric pneumonia: a time-stratified case–crossover study in an urban area
Pneumonia, the leading reason underlying childhood deaths, may be triggered or exacerbated by air pollution. To date, only a few studies have examined the association of air pollution with emergency department...Environmental Health 2019 18:77Published on: 28 August 2019Neurocognitive impact of metal exposure and social stressors among schoolchildren in Taranto, Italy
Metal exposure is a public health hazard due to neurocognitive effects starting in early life. Poor socio-economic status, adverse home and family environment can enhance the neurodevelopmental toxicity due to...Environmental Health 2019 18:67Published on: 19 July 2019Prenatal plasma concentrations of Perfluoroalkyl and polyfluoroalkyl substances and neuropsychological development in children at four years of age
Perfluoroalkyl and polyfluoroalkyl substances (PFASs) are persistent pollutants and have endocrine disruptive and neurotoxic effects. The association between maternal PFAS concentrations and neuropsychological...Environmental Health 2019 18:53Published on: 13 June 2019Exposure to arsenic in utero is associated with various types of DNA damage and micronuclei in newborns: a birth cohort study
Growing evidence indicates that in utero arsenic exposures in humans may increase the risk of adverse health effects and development of diseases later in life. This study aimed to evaluate potential health ris...Environmental Health 2019 18:51Published on: 7 June 2019The Correction to this article has been published in Environmental Health 2019 18:68Relations between air pollution and vascular development in 5-year old children: a cross-sectional study in the Netherlands
Air pollution has been shown to promote cardiovascular disease in adults. Possible mechanisms include air pollution induced changes in arterial wall function and structure. Atherosclerotic vascular disease is ...Environmental Health 2019 18:50Published on: 16 May 2019Maternal exposure to ambient fine particulate matter and fetal growth in Shanghai, China
Fetal growth restriction (FGR) is not only a major determinant of perinatal morbidity and mortality but also leads to adverse health effects in later life. Over the past decade, numerous studies have indicated...Environmental Health 2019 18:49Published on: 16 May 2019- Environmental Health 2019 18:32Published on: 11 April 2019
Fluoride exposure and pubertal development in children living in Mexico City
Previous animal and ecological studies have provided evidence for an earlier sexual maturation in females in relation to fluoride exposure; however, no epidemiological studies have examined the association bet...Environmental Health 2019 18:26Published on: 29 March 2019Urinary mycoestrogens and age and height at menarche in New Jersey girls
Despite evidence of the endocrine disrupting properties of zearalenone (ZEN) and alpha-zearalanol (zeranol, α-ZAL), they have been minimally studied in human populations. In previous cross-sectional analyses, ...Environmental Health 2019 18:24Published on: 22 March 2019Exposure to prenatal secondhand smoke and early neurodevelopment: Mothers and Children’s Environmental Health (MOCEH) study
The association between exposure to secondhand smoke (SHS) during pregnancy and a child’s neurodevelopment has not been established yet. We explored the association between prenatal exposure to SHS and neurode...Environmental Health 2019 18:22Published on: 20 March 2019- Environmental Health 2019 18:21Published on: 15 March 2019The Correction to this article has been published in Environmental Health 2019 18:47The Letter to the Editor Response to this article has been published in Environmental Health 2019 18:29The original article was published in Environmental Health 2018 17:77
Prenatal arsenic exposure alters the placental expression of multiple epigenetic regulators in a sex-dependent manner
Prenatal exposure to arsenic has been linked to a range of adverse health conditions in later life. Such fetal origins of disease are frequently the result of environmental effects on the epigenome, leading to...Environmental Health 2019 18:18Published on: 28 February 2019Polyunsaturated fatty acids and child neurodevelopment among a population exposed to DDT: a cohort study
Child neurodevelopment has been positively linked to maternal intake of polyunsaturated fatty acids (PUFAs) during pregnancy; however, it is unknown if that relationship persists among populations exposed to e...Environmental Health 2019 18:17Published on: 28 February 2019The CDC blood lead reference value for children: time for a change
The purpose of this article is to consider alternate uses of the blood lead reference value for children. There are two possible approaches. Historically the reference value has been used to guide clinical and...Environmental Health 2019 18:16Published on: 28 February 2019Prenatal exposure to extremely low frequency magnetic field and its impact on fetal growth
Studies on the effect of prenatal exposure to magnetic field (MF) on fetal growth is inconclusive and subject to some methodological limitations, particularly in measurement of MF exposure. The present study a...Environmental Health 2019 18:6Published on: 11 January 2019Very low-level prenatal mercury exposure and behaviors in children: the HOME Study
Mercury is toxic to the developing brain, but the lowest concentration associated with the development of behavior problems is unclear. The purpose of this study was to examine the association between very low...Environmental Health 2019 18:4Published on: 9 January 2019Air pollution in the week prior to delivery and preterm birth in 24 Canadian cities: a time to event analysis
Numerous studies have examined the association between air pollution and preterm birth (< 37 weeks gestation) but findings have been inconsistent. These associations may be more difficult to detect than associ...Environmental Health 2019 18:1Published on: 3 January 2019Maternal urinary 2-hydroxynaphthalene and birth outcomes in Taiyuan, China
Naphthalene is the simplest polycyclic aromatic hydrocarbon (PAH). It is easily emitted into the atmosphere, posing a significant risk to human health. However, limited studies have described the impact of nap...Environmental Health 2018 17:91Published on: 20 December 2018Associations of greenness, greyness and air pollution exposure with children’s health: a cross-sectional study in Southern Italy
Due to the complex interplay among different urban-related exposures, a comprehensive approach is advisable to estimate the health effects. We simultaneously assessed the effect of “green”, “grey” and air poll...Environmental Health 2018 17:86Published on: 5 December 2018Longitudinal associations of in utero and early life near-roadway air pollution with trajectories of childhood body mass index
Evidence suggests that childhood near-roadway air pollution (NRAP) exposures contribute to increased body mass index (BMI); however, effects of NRAP exposure during the vulnerable periods including in utero and f...Environmental Health 2018 17:64Published on: 14 September 2018Environmental pollution and social factors as contributors to preterm birth in Fresno County
Environmental pollution exposure during pregnancy has been identified as a risk factor for preterm birth. Most studies have evaluated exposures individually and in limited study populations.Environmental Health 2018 17:70Published on: 29 August 2018Occupational exposure to organic solvents during pregnancy and childhood behavior: findings from the PELAGIE birth cohort (France, 2002–2013)
Numerous industries use organic solvents, and many workers from various occupational sectors are exposed to these known neurotoxicants, including pregnant women. Our objective is to explore whether occupationa...Environmental Health 2018 17:63Published on: 27 July 2018The Correction to this article has been published in Environmental Health 2018 17:71Air pollution and airway resistance at age 8 years – the PIAMA birth cohort study
Air pollution has been found to adversely affect children’s lung function. Forced expiratory volume in 1 s and forced vital capacity from spirometry have been studied most frequently, but measurements of airwa...Environmental Health 2018 17:61Published on: 17 July 2018Applying methods of the global burden of diseases, injuries, and risk factors study to developmental neurotoxicants: a commentary
The purpose of this commentary is to consider whether the methods of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) can provide accurate estimates of the impact of developmental neurotox...Environmental Health 2018 17:53Published on: 4 June 2018Reporting to parents on children’s exposures to asthma triggers in low-income and public housing, an interview-based case study of ethics, environmental literacy, individual action, and public health benefits
Emerging evidence about the effects of endocrine disruptors on asthma symptoms suggests new opportunities to reduce asthma by changing personal environments. Right-to-know ethics supports returning personal re...Environmental Health 2018 17:48Published on: 21 May 2018Early life swimming pool exposure and asthma onset in children – a case-control study
Trichloramine exposure in indoor swimming pools has been suggested to cause asthma in children. We aimed to investigate the risk of asthma onset among children in relation to individual trichloramine exposure.Environmental Health 2018 17:34Published on: 11 April 2018Childhood and adolescent phenol and phthalate exposure and the age of menarche in Latina girls
The age of menarche has been associated with metabolic and cardiovascular disease, as well as cancer risk. The decline in menarcheal age over the past century may be partially attributable to increased exposur...Environmental Health 2018 17:32Published on: 3 April 2018Early-life exposure to PM2.5 and risk of acute asthma clinical encounters among children in Massachusetts: a case-crossover analysis
Associations between ambient particulate matter < 2.5 μm (PM2.5) and asthma morbidity have been suggested in previous epidemiologic studies but results are inconsistent for areas with lower PM2.5 levels. We estim...Environmental Health 2018 17:20Published on: 21 February 2018The Correction to this article has been published in Environmental Health 2018 17:25Transgenerational effects of polychlorinated biphenyls: 1. Development and physiology across 3 generations of rats
Polychlorinated biphenyls (PCBs) are persistent organic environmental contaminants and known endocrine-disrupting chemicals (EDCs). Previous studies demonstrated that developmental exposure to the weakly estro...Environmental Health 2018 17:18Published on: 20 February 2018Prenatal exposure to persistent organic pollutants and child overweight/obesity at 5-year follow-up: a prospective cohort study
Prenatal exposure to persistent organic pollutants (POPs), may influence offspring weight gain. More prospective epidemiological studies are needed to compliment the growing body of evidence from animal studies.Environmental Health 2018 17:9Published on: 18 January 2018Prenatal exposure to perfluoroalkyl and polyfluoroalkyl substances and childhood atopic dermatitis: a prospective birth cohort study
Perfluoroalkyl and polyfluoroalkyl substances (PFASs) have been reported to suppress immune function. However, previous studies on prenatal exposure to PFASs and allergic disorders in offspring provided incons...Environmental Health 2018 17:8Published on: 17 January 2018Road traffic noise and children’s inattention
An increasing number of children are exposed to road traffic noise levels that may lead to adverse effects on health and daily functioning. Childhood is a period of intense growth and brain maturation, and chi...Environmental Health 2017 16:127Published on: 21 November 2017Genetic and epigenetic susceptibility of airway inflammation to PM2.5 in school children: new insights from quantile regression
The fractional concentration of exhaled nitric oxide (FeNO) is a biomarker of airway inflammation that has proved to be useful in investigations of genetic and epigenetic airway susceptibility to ambient air p...Environmental Health 2017 16:88Published on: 18 August 2017Maternal occupational exposure and oral clefts in offspring
Previous studies suggest that periconceptional maternal occupational exposure to solvents and pesticides increase the risk of oral clefts in the offspring. Less is known about the effect of occupational exposu...Environmental Health 2017 16:83Published on: 4 August 2017Genome-wide gene by lead exposure interaction analysis identifies UNC5D as a candidate gene for neurodevelopment
Neurodevelopment is a complex process involving both genetic and environmental factors. Prenatal exposure to lead (Pb) has been associated with lower performance on neurodevelopmental tests. Adverse neurodevel...Environmental Health 2017 16:81Published on: 28 July 2017Urinary bisphenol A and pubertal development in Chinese school-aged girls: a cross-sectional study
Animal studies suggest that bisphenol A (BPA) may perturb pubertal development in females. However, evidence from human studies is limited.Environmental Health 2017 16:80Published on: 27 July 2017Prenatal and postnatal bisphenol A exposure and social impairment in 4-year-old children
Prenatal and postnatal exposure to bisphenol A (BPA) may affect early brain development. Rodent studies suggest that prenatal and postnatal neurodevelopmental toxicity from BPA exposure may manifest as social ...Environmental Health 2017 16:79Published on: 26 July 2017Impact of phthalate and BPA exposure during in utero windows of susceptibility on reproductive hormones and sexual maturation in peripubertal males
Phthalates and BPA are endocrine disrupting chemicals (EDCs) widely used in consumer products. Evidence suggests that phthalate and BPA exposure alters steroid hormone levels in adults, while in utero exposure...Environmental Health 2017 16:69Published on: 21 June 2017The aquaglyceroporin AQP9 contributes to the sex-specific effects of in utero arsenic exposure on placental gene expression
Sex-specific factors play a major role in human health and disease, including responses to environmental stresses such as toxicant exposure. Increasing evidence suggests that such sex differences also exist du...Environmental Health 2017 16:59Published on: 14 June 2017Mobile phone use, school electromagnetic field levels and related symptoms: a cross-sectional survey among 2150 high school students in Izmir
Health outcomes of electromagnetic fields (EMF) from mobile phones and their base stations are of concern. Conducting multidisciplinary research, targeting children and exploring dose-response are recommended....Environmental Health 2017 16:51Published on: 2 June 2017Genome-wide DNA methylation at birth in relation to in utero arsenic exposure and the associated health in later life
In utero arsenic exposure may alter fetal developmental programming by altering DNA methylation, which may result in a higher risk of disease in later life. We evaluated the association between in utero arseni...Environmental Health 2017 16:50Published on: 30 May 2017Prenatal bisphenol a exposure and dysregulation of infant hypothalamic-pituitary-adrenal axis function: findings from the APrON cohort study
Animal models show that prenatal bisphenol A (BPA) exposure leads to sexually dimorphic disruption of the neuroendocrine system in offspring, including the hypothalamic-pituitary-adrenal (HPA) neuroendocrine s...Environmental Health 2017 16:47Published on: 19 May 2017Distributions and determinants of urinary biomarkers of organophosphate pesticide exposure in a prospective Spanish birth cohort study
Prenatal exposure to organophosphate pesticides (OPs) has been associated with impaired child development. Pesticide exposure determinants need to be studied in order to identify sources and pathways of pestic...Environmental Health 2017 16:46Published on: 17 May 2017Ozone and childhood respiratory disease in three US cities: evaluation of effect measure modification by neighborhood socioeconomic status using a Bayesian hierarchical approach
Ground-level ozone is a potent airway irritant and a determinant of respiratory morbidity. Susceptibility to the health effects of ambient ozone may be influenced by both intrinsic and extrinsic factors, such ...Environmental Health 2017 16:36Published on: 5 April 2017The Erratum to this article has been published in Environmental Health 2017 16:63The mouse mammary gland as a sentinel organ: distinguishing ‘control’ populations with diverse environmental histories
There are numerous examples of laboratory animals that were inadvertently exposed to endocrine disrupting chemicals (EDCs) during the process of conducting experiments. Controlling contaminations in the labora...Environmental Health 2017 16:25Published on: 9 March 2017Exposure to phthalates and bisphenol A are associated with atopic dermatitis symptoms in children: a time-series analysis
Despite increasing evidence on the relationship between exposure to phthalates and bisphenol A with allergies and asthma, reports on atopic dermatitis (AD) with these chemicals are few. We assessed the associa...Environmental Health 2017 16:24Published on: 9 March 2017Cross-sectional study of social behaviors in preschool children and exposure to flame retardants
Children are exposed to flame retardants from the built environment. Brominated diphenyl ethers (BDE) and organophosphate-based flame retardants (OPFRs) are associated with poorer neurocognitive functioning in...Environmental Health 2017 16:23Published on: 9 March 2017Meeting report: the 5th International expert symposium in Fukushima on radiation and health
The symposium entitled “Chernobyl +30, Fukushima +5: Lessons and Solutions for Fukushima’s Thyroid Question” was held in September, 2016 in Fukushima. The aim of the Symposium was to revisit and recapitulate e...Environmental Health 2017 16:3Published on: 18 January 2017
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