Progress in refining the clinical management of cancer of unknown primary in the molecular era
E Rassy et al, Nature Rev Clin Oncology, April 2020
E Rassy et al, Nature Rev Clin Oncology, April 2020
In this Review, we discuss the clinical management of cancer of unknown primary (CUP) in the era of precision medicine. We focus on the advances in understanding the biology of CUP, the implications for the diagnosis and classification of CUP according to the tissue of origin and the shift away from empirical therapy towards tailored therapy.
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