viernes, 29 de mayo de 2020

Activation of TGR5 protects blood brain barrier via the BRCA1/Sirt1 pathway after middle cerebral artery occlusion in rats | Journal of Biomedical Science | Full Text

Activation of TGR5 protects blood brain barrier via the BRCA1/Sirt1 pathway after middle cerebral artery occlusion in rats | Journal of Biomedical Science | Full Text

The disruption of the blood–brain barrier (BBB) plays a critical event in the pathogenesis of ischemia stroke. TGR5 is recognized as a potential target for the treatment for neurologic disorders.
Authors:Hui Liang, Nate Matei, Devin W. McBride, Yang Xu, Jiping Tang, Benyan Luo and John H. Zhang
Citation:Journal of Biomedical Science 2020 27:61
Content type:Research
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