Coronavirus [NEW TOPIC PAGE]

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 Coronavirus

COVID-19 and Postinfection Immunity- Limited Evidence, Many Remaining Questions
RD Kircaldy et al, JAMA< May 11, 2020

Coronavirus COVID-19 Existing limited data on antibody responses to SARS-CoV-2 and related coronaviruses, as well as one small animal model study, suggest that recovery from COVID-19 might confer immunity against reinfection, at least temporarily. However, the immune response to COVID-19 is not yet fully understood and definitive data on postinfection immunity are lacking.

Applying principles of behaviour change to reduce SARS-CoV-2 transmission
R West et al, Nature Human Behavior, May 2020

There is an urgent need for direct evidence to inform development of behavioral interventions, but it is possible to make a start by applying behavioral science methods and models

Reading the pandemic data
JM Zacks et al. Science blog, May 12, 2020

Understanding the spread of COVID-19 requires understanding nonlinear growth. Whereas linear growth is intuitive, nonlinear growth is not. People’s predictions for nonlinear patterns tend to be closer to linear projections, assuming that future growth will be similar to that of the past. For a pandemic, this can lead to dangerous underestimation.

Interpreting a covid-19 test result
J Watson et al, BMJ, May 12, 2020

The result of a test for covid-19 depends on the accuracy of the test, and the pre-test probability or estimated risk of disease before testing. A positive RT-PCR test has more weight than a negative test because of the test’s high specificity but moderate sensitivity. A single negative test should not be used as a rule-out in patients with suggestive symptoms.

Deep learning models for COVID-19 infected area segmentation in CT images
A Voulodimous et al, MEDRXIV, May 11, 2020

Racial and Ethnic Disparities in Population Level Covid-19 Mortality
CP Gross et al, MEDRXIV, May 11, 2020

Mobility trends provide a leading indicator of changes in SARS-CoV-2 transmission
AC Miller et al, MEDRXIV, May 11, 2020

COVID-19 diagnosis prediction by symptoms of tested individuals: a machine learning approach
Y Zaobi et al, MEDRXIV, May 11, 2020

Social Distancing is Effective at Mitigating COVID-19 Transmission in the United States
H Badr et al, MEDRIV, May 11, 2020