Gut Bacteria Affecting Parkinson’s Treatment
Parkinson’s disease (PD) is treated by levodopa, which is a prodrug capable of crossing the blood-brain barrier before being metabolized to dopamine, a vital neurotransmitter in the brain.
However, certain gut bacteria interfere with this treatment, leading to unpredictable fluctuations in the motor response to levodopa and pushing up the dosage levels unnecessarily.
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