Pancreatic Cancer
Pancreatic Cancer: Recent Genomic Insights - August 24, 2015
Check out genetic conditions and tests associated with pancreatic cancer,
from the NIH Genetic Testing Registry
Identification of patients with family history of pancreatic cancer - investigation of an NLP system portability.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sxXumhA0XhqAQe-hpLoK75Gyq9-v-u71VvR2bJtPKvm5vpwZxiV8uusAW0r1K_c9XSTb6xnvITXkH9t7QIGC8PmczeMr6n8f0sHMejQSA3xtjWv6z8XY8r=s0-d)
Mehrabi S et al. Stud Health Technol Inform 2015 216604-8
Mehrabi S et al. Stud Health Technol Inform 2015 216604-8
In a former first family, cancer has a grim legacy,
by D Grady, New York Times, Aug 7
Screening for pancreatic cancer in familial high-risk individuals: A systematic review.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sxXumhA0XhqAQe-hpLoK75Gyq9-v-u71VvR2bJtPKvm5vpwZxiV8uusAW0r1K_c9XSTb6xnvITXkH9t7QIGC8PmczeMr6n8f0sHMejQSA3xtjWv6z8XY8r=s0-d)
Lu C et al. World J. Gastroenterol. 2015 Jul 28. 21(28) 8678-86
Lu C et al. World J. Gastroenterol. 2015 Jul 28. 21(28) 8678-86
Genomic research advances pancreatic cancer’s early detection and treatment![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sxXumhA0XhqAQe-hpLoK75Gyq9-v-u71VvR2bJtPKvm5vpwZxiV8uusAW0r1K_c9XSTb6xnvITXkH9t7QIGC8PmczeMr6n8f0sHMejQSA3xtjWv6z8XY8r=s0-d)
V Brower, JNCI, July 2015
V Brower, JNCI, July 2015
PanGen-Fam: Spanish registry of hereditary pancreatic cancer.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sxXumhA0XhqAQe-hpLoK75Gyq9-v-u71VvR2bJtPKvm5vpwZxiV8uusAW0r1K_c9XSTb6xnvITXkH9t7QIGC8PmczeMr6n8f0sHMejQSA3xtjWv6z8XY8r=s0-d)
Mocci E et al. Eur. J. Cancer 2015 Jul 23.
Mocci E et al. Eur. J. Cancer 2015 Jul 23.
Glypican-1 identifies cancer exosomes and detects early pancreatic cancer.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sxXumhA0XhqAQe-hpLoK75Gyq9-v-u71VvR2bJtPKvm5vpwZxiV8uusAW0r1K_c9XSTb6xnvITXkH9t7QIGC8PmczeMr6n8f0sHMejQSA3xtjWv6z8XY8r=s0-d)
Melo SA et al. Nature 2015 Jun 24.
Melo SA et al. Nature 2015 Jun 24.
A perfect blood test for pancreatic cancer?
By Elaine Schattner, Forbes, Jul 6
A step closer to screening for curable pancreatic cancer? ![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sxXumhA0XhqAQe-hpLoK75Gyq9-v-u71VvR2bJtPKvm5vpwZxiV8uusAW0r1K_c9XSTb6xnvITXkH9t7QIGC8PmczeMr6n8f0sHMejQSA3xtjWv6z8XY8r=s0-d)
Marcia I. Canto, Nature Reviews Gastroenterology, June 30, 2014
Marcia I. Canto, Nature Reviews Gastroenterology, June 30, 2014
New biomarker for pancreatic cancer?
By R Bazeley, PHG Foundation, June 29, 2015
Common variation at 2p13.3, 3q29, 7p13 and 17q25.1 associated with susceptibility to pancreatic cancer![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sxXumhA0XhqAQe-hpLoK75Gyq9-v-u71VvR2bJtPKvm5vpwZxiV8uusAW0r1K_c9XSTb6xnvITXkH9t7QIGC8PmczeMr6n8f0sHMejQSA3xtjWv6z8XY8r=s0-d)
Childs E et al. Nature Genetics, June 22, 2015
Childs E et al. Nature Genetics, June 22, 2015
Gene-by-environment interactions in pancreatic cancer: Implications for prevention.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sxXumhA0XhqAQe-hpLoK75Gyq9-v-u71VvR2bJtPKvm5vpwZxiV8uusAW0r1K_c9XSTb6xnvITXkH9t7QIGC8PmczeMr6n8f0sHMejQSA3xtjWv6z8XY8r=s0-d)
Jansen RJ et al. Yale J Biol Med 2015 Jun (2) 115-126
Jansen RJ et al. Yale J Biol Med 2015 Jun (2) 115-126
The TERT gene harbors multiple variants associated with pancreatic cancer susceptibility.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sxXumhA0XhqAQe-hpLoK75Gyq9-v-u71VvR2bJtPKvm5vpwZxiV8uusAW0r1K_c9XSTb6xnvITXkH9t7QIGC8PmczeMr6n8f0sHMejQSA3xtjWv6z8XY8r=s0-d)
Campa D et al. Int. J. Cancer 2015 May 4.
Campa D et al. Int. J. Cancer 2015 May 4.
Genetics: New genomic alterations detected in pancreatic cancer.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sxXumhA0XhqAQe-hpLoK75Gyq9-v-u71VvR2bJtPKvm5vpwZxiV8uusAW0r1K_c9XSTb6xnvITXkH9t7QIGC8PmczeMr6n8f0sHMejQSA3xtjWv6z8XY8r=s0-d)
Nat Rev Clin Oncol 2015 Mar 24.
Nat Rev Clin Oncol 2015 Mar 24.
Whole genomes redefine the mutational landscape of pancreatic cancer.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sxXumhA0XhqAQe-hpLoK75Gyq9-v-u71VvR2bJtPKvm5vpwZxiV8uusAW0r1K_c9XSTb6xnvITXkH9t7QIGC8PmczeMr6n8f0sHMejQSA3xtjWv6z8XY8r=s0-d)
Waddell Nicola et al. Nature 2015 Feb 26. (7540) 495-501
Waddell Nicola et al. Nature 2015 Feb 26. (7540) 495-501
Pancreatic cancer and FOLFIRINOX: a new era and new questions.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sxXumhA0XhqAQe-hpLoK75Gyq9-v-u71VvR2bJtPKvm5vpwZxiV8uusAW0r1K_c9XSTb6xnvITXkH9t7QIGC8PmczeMr6n8f0sHMejQSA3xtjWv6z8XY8r=s0-d)
Marsh Robert De W et al. Cancer Med 2015 Feb 19.
Marsh Robert De W et al. Cancer Med 2015 Feb 19.
RNA-Seq SSRs and small RNA-Seq SSRs: New approaches in cancer biomarker discovery.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sxXumhA0XhqAQe-hpLoK75Gyq9-v-u71VvR2bJtPKvm5vpwZxiV8uusAW0r1K_c9XSTb6xnvITXkH9t7QIGC8PmczeMr6n8f0sHMejQSA3xtjWv6z8XY8r=s0-d)
Alisoltani Arghavan et al. Gene 2015 Apr 10. (1) 34-43
Alisoltani Arghavan et al. Gene 2015 Apr 10. (1) 34-43
A genome-wide investigation of microRNA expression identifies biologically-meaningful microRNAs that distinguish between high-risk and low-risk intraductal papillary mucinous neoplasms of the pancreas.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sxXumhA0XhqAQe-hpLoK75Gyq9-v-u71VvR2bJtPKvm5vpwZxiV8uusAW0r1K_c9XSTb6xnvITXkH9t7QIGC8PmczeMr6n8f0sHMejQSA3xtjWv6z8XY8r=s0-d)
Permuth-Wey Jennifer et al. PLoS ONE 2015 (1) e0116869
Permuth-Wey Jennifer et al. PLoS ONE 2015 (1) e0116869
Epigenetic Silencing of GNMT gene in pancreatic adenocarcinoma.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sxXumhA0XhqAQe-hpLoK75Gyq9-v-u71VvR2bJtPKvm5vpwZxiV8uusAW0r1K_c9XSTb6xnvITXkH9t7QIGC8PmczeMr6n8f0sHMejQSA3xtjWv6z8XY8r=s0-d)
Botezatu Anca et al. Cancer Genomics Proteomics 0 (1) 21-30
Botezatu Anca et al. Cancer Genomics Proteomics 0 (1) 21-30
Phenome-genome association studies of pancreatic cancer: new targets for therapy and diagnosis.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sxXumhA0XhqAQe-hpLoK75Gyq9-v-u71VvR2bJtPKvm5vpwZxiV8uusAW0r1K_c9XSTb6xnvITXkH9t7QIGC8PmczeMr6n8f0sHMejQSA3xtjWv6z8XY8r=s0-d)
Narayanan Ramaswamy et al. Cancer Genomics Proteomics 0 (1) 9-19
Narayanan Ramaswamy et al. Cancer Genomics Proteomics 0 (1) 9-19
Low Frequency of KRAS mutation in pancreatic ductal adenocarcinomas in Korean patients and its prognostic value.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sxXumhA0XhqAQe-hpLoK75Gyq9-v-u71VvR2bJtPKvm5vpwZxiV8uusAW0r1K_c9XSTb6xnvITXkH9t7QIGC8PmczeMr6n8f0sHMejQSA3xtjWv6z8XY8r=s0-d)
Kwon Mi Jung et al. Pancreas 2014 Dec 15.
Kwon Mi Jung et al. Pancreas 2014 Dec 15.
Transcriptional profiling reveals functional links between RasGrf1 and Pttg1 in pancreatic beta cells.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sxXumhA0XhqAQe-hpLoK75Gyq9-v-u71VvR2bJtPKvm5vpwZxiV8uusAW0r1K_c9XSTb6xnvITXkH9t7QIGC8PmczeMr6n8f0sHMejQSA3xtjWv6z8XY8r=s0-d)
Manyes Lara et al. BMC Genomics 2014 1019
Manyes Lara et al. BMC Genomics 2014 1019
Pancreatic cancer genomics: where can the science take us?![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sxXumhA0XhqAQe-hpLoK75Gyq9-v-u71VvR2bJtPKvm5vpwZxiV8uusAW0r1K_c9XSTb6xnvITXkH9t7QIGC8PmczeMr6n8f0sHMejQSA3xtjWv6z8XY8r=s0-d)
Graham J S et al. Clin. Genet. 2014 Nov 12.
Graham J S et al. Clin. Genet. 2014 Nov 12.
Biomarkers for pancreatic cancer: recent achievements in proteomics and genomics through classical and multivariate statistical methods.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sxXumhA0XhqAQe-hpLoK75Gyq9-v-u71VvR2bJtPKvm5vpwZxiV8uusAW0r1K_c9XSTb6xnvITXkH9t7QIGC8PmczeMr6n8f0sHMejQSA3xtjWv6z8XY8r=s0-d)
Marengo Emilio et al. World J. Gastroenterol. 2014 Oct 7. (37) 13325-42
Marengo Emilio et al. World J. Gastroenterol. 2014 Oct 7. (37) 13325-42
Transcriptome analysis of pancreatic cancer reveals a tumor suppressor function for HNF1A.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sxXumhA0XhqAQe-hpLoK75Gyq9-v-u71VvR2bJtPKvm5vpwZxiV8uusAW0r1K_c9XSTb6xnvITXkH9t7QIGC8PmczeMr6n8f0sHMejQSA3xtjWv6z8XY8r=s0-d)
Hoskins Jason W et al. Carcinogenesis 2014 Dec (12) 2670-8
Hoskins Jason W et al. Carcinogenesis 2014 Dec (12) 2670-8
Leukocyte telomere length in relation to pancreatic cancer risk: a prospective study.![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sxXumhA0XhqAQe-hpLoK75Gyq9-v-u71VvR2bJtPKvm5vpwZxiV8uusAW0r1K_c9XSTb6xnvITXkH9t7QIGC8PmczeMr6n8f0sHMejQSA3xtjWv6z8XY8r=s0-d)
Campa Daniele et al. Cancer Epidemiol. Biomarkers Prev. 2014 Nov (11) 2447-54
Campa Daniele et al. Cancer Epidemiol. Biomarkers Prev. 2014 Nov (11) 2447-54
Pancreatic Cancer: Recent Genomic Insights - August 7, 2014
New findings: Genome-wide association study identifies multiple susceptibility loci for pancreatic cancer.
Brian M Wolpin et al. Nature Genetics, August 3, 3014
Brian M Wolpin et al. Nature Genetics, August 3, 3014
What is pancreatic cancer and can it be prevented?
Information from the National Cancer Institute
Risk factors for pancreatic cancer include smoking, age, obesity, and genetics.
Information from the American Cancer Society
Pancreatic cancer genomics.
Chang DK et al,. Curr Opin Genet Dev. 2014 Feb;24:74-81.
Chang DK et al,. Curr Opin Genet Dev. 2014 Feb;24:74-81.
Pancreatic cancer genomics: insights and opportunities for clinical translation![External Web Site Icon External Web Site Icon](https://lh3.googleusercontent.com/blogger_img_proxy/AEn0k_sxXumhA0XhqAQe-hpLoK75Gyq9-v-u71VvR2bJtPKvm5vpwZxiV8uusAW0r1K_c9XSTb6xnvITXkH9t7QIGC8PmczeMr6n8f0sHMejQSA3xtjWv6z8XY8r=s0-d)
Alvin Makohon-Moore et al. Genome Medicine (2013)
Did you know? There are >420 genes reported in relation to risk and outcomes of pancreatic cancer, including 20 genomewide association studies.
Visit the HuGE Navigator
Alvin Makohon-Moore et al. Genome Medicine (2013)
Did you know? There are >420 genes reported in relation to risk and outcomes of pancreatic cancer, including 20 genomewide association studies.
Find out what genetic disorders and tests are associated with pancreatic cancer,
from the NIH Genetic Testing Registry
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