Alpha-synuclein-induced mitochondrial dysfunction is mediated via a sirtuin 3-dependent pathway | Molecular Neurodegeneration | Full Text

Alpha-synuclein-induced mitochondrial dysfunction is mediated via a sirtuin 3-dependent pathway | Molecular Neurodegeneration | Full Text

Alpha-synuclein-induced mitochondrial dysfunction is mediated via a sirtuin 3-dependent pathway

Misfolding and aggregation of the presynaptic protein alpha-synuclein (αsyn) is a hallmark of Parkinson’s disease (PD) and related synucleinopathies. Although predominantly localized in the cytosol, a body of ...

Authors:Jae-Hyeon Park, Jeremy D. Burgess, Ayman H. Faroqi, Natasha N. DeMeo, Fabienne C. Fiesel, Wolfdieter Springer, Marion Delenclos and Pamela J. McLean

Citation:Molecular Neurodegeneration 2020 15:5

Content type:Research article

Published on: 13 January 2020

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