Novel deep intronic mutation in the coagulation factor XIII a chain gene leading to unexpected RNA splicing in a patient with factor XIII deficiency | BMC Medical Genetics | Full Text

Novel deep intronic mutation in the coagulation factor XIII a chain gene leading to unexpected RNA splicing in a patient with factor XIII deficiency | BMC Medical Genetics | Full Text

Novel deep intronic mutation in the coagulation factor XIII a chain gene leading to unexpected RNA splicing in a patient with factor XIII deficiency

Coagulation factor XIII (FXIII) plays an essential role in maintaining hemostasis by crosslinking fibrin. Deficiency in FXIII affects clot stability and increases the risk of severe bleeding. Congenital FXIII ...

Authors:Jun Deng, Dan Li, Heng Mei, Liang Tang, Hua-fang Wang and Yu Hu

Citation:BMC Medical Genetics 2020 21:9

Content type:Research article

Published on: 8 January 2020

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