Silencing or inhibition of H3K79 methyltransferase DOT1L induces cell cycle arrest by epigenetically modulating c-Myc expression in colorectal cancer | Clinical Epigenetics | Full Text

Silencing or inhibition of H3K79 methyltransferase DOT1L induces cell cycle arrest by epigenetically modulating c-Myc expression in colorectal cancer | Clinical Epigenetics | Full Text

Silencing or inhibition of H3K79 methyltransferase DOT1L induces cell cycle arrest by epigenetically modulating c-Myc expression in colorectal cancer

Epigenetic regulations play pivotal roles in tumorigenesis and cancer development. Disruptor of telomeric silencing-1-like (DOT1L), also known as KMT4, is the only identified histone methyltransferase that cat...

Authors:Liqun Yang, Qian Lei, Lin Li, Jie Yang, Zhen Dong and Hongjuan Cui

Citation:Clinical Epigenetics 2019 11:199

Content type:Research

Published on: 30 December 2019

• ViewFull Text
 
• ViewPDF