domingo, 26 de enero de 2020

Silencing or inhibition of H3K79 methyltransferase DOT1L induces cell cycle arrest by epigenetically modulating c-Myc expression in colorectal cancer | Clinical Epigenetics | Full Text

Silencing or inhibition of H3K79 methyltransferase DOT1L induces cell cycle arrest by epigenetically modulating c-Myc expression in colorectal cancer | Clinical Epigenetics | Full Text

Epigenetic regulations play pivotal roles in tumorigenesis and cancer development. Disruptor of telomeric silencing-1-like (DOT1L), also known as KMT4, is the only identified histone methyltransferase that cat...
Authors:Liqun Yang, Qian Lei, Lin Li, Jie Yang, Zhen Dong and Hongjuan Cui
Citation:Clinical Epigenetics 2019 11:199
Content type:Research
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