Colorectal Cancer
Colorectal Cancer: Genetics and Family History Insights - August 4, 2015
CDC Info
- Check out the CDC evidence table on tiered classification of genomic tests for colorectal cancer
- Genetic testing for hereditary colorectal cancer
- March is Colorectal Cancer Awareness
- Screen for Life: National Colorectal Cancer Action Campaign
- Colorectal Cancer Awareness
- Listen to a CDC podcast about genetic testing for Lynch syndrome
- Colorectal cancer screening tests
Performance characteristics of next-generation sequencing in clinical mutation detection of colorectal cancers.
Haley L et al. Mod. Pathol. 2015 Jul 31.
Haley L et al. Mod. Pathol. 2015 Jul 31.
Familial colorectal cancer risk may be lower than previously thought: A Danish cohort study.
Lautrup CK et al. Cancer Epidemiol 2015 Jul 26.
Lautrup CK et al. Cancer Epidemiol 2015 Jul 26.
High prevalence of hereditary cancer syndromes in adolescents and young adults with colorectal cancer
Mork ME.et al. J Clinical Oncology, July 20, 2015
Mork ME.et al. J Clinical Oncology, July 20, 2015
Study finds one-third of colorectal cancers diagnosed before age 35 are hereditary, Newswire, Jul 20
Newswire, Jul 20
Increased risk of colorectal cancer among family members of all ages, regardless of age of index case at diagnosis.
Samadder NJ et al. Clin. Gastroenterol. Hepatol. 2015 Jul 15.
Samadder NJ et al. Clin. Gastroenterol. Hepatol. 2015 Jul 15.
Genetic architecture of colorectal cancer.
Peters U et al. Gut 2015 Jul 17.
Peters U et al. Gut 2015 Jul 17.
MAD1L1 Arg558His and MAD2L1 Leu84Met interaction with smoking increase the risk of colorectal cancer.
Zhong R et al. Sci Rep 2015 12202
Zhong R et al. Sci Rep 2015 12202
Mosaic epigenetic inheritance as a cause of early-onset colorectal cancer.
Sloane MA et al. JAMA Oncol 2015 Jun 11.
Sloane MA et al. JAMA Oncol 2015 Jun 11.
Genome-wide association study of colorectal cancer identifies six new susceptibility loci.
Schumacher FR et al. Nat Commun 2015 7138
Schumacher FR et al. Nat Commun 2015 7138
Genetics, diagnosis and management of colorectal cancer (Review).
De Rosa M et al. Oncol. Rep. 2015 Jul 3.
De Rosa M et al. Oncol. Rep. 2015 Jul 3.
A prospective Six Sigma quality improvement trial to optimize universal screening for genetic syndrome among patients with young-onset colorectal cancer.
Dineen S et al. J Natl Compr Canc Netw 2015 Jul (7) 865-72
Dineen S et al. J Natl Compr Canc Netw 2015 Jul (7) 865-72
Colorectal Cancer: Public Health and Genomic Insights - May 18, 2015
Special Supplement: Colorectal cancer is the world?s fourth most deadly cancer, killing almost 700,000 people every year
Nature Outlook, May 2015
Nature Outlook, May 2015
Colorectal cancer: 5 big questions
Chadkrahar S , Nature Outlook, May 2015
Chadkrahar S , Nature Outlook, May 2015
Prevention: Tending the gut
Gravitz L , Nature Outlook, May 2015
Gravitz L , Nature Outlook, May 2015
Screening: Early alert
Willyard C , Nature Outlook, May 2015
Willyard C , Nature Outlook, May 2015
Microbiome: Microbial mystery
DeWeerdt S , Nature Outlook, May 2015
DeWeerdt S , Nature Outlook, May 2015
A subset of genetic susceptibility variants for colorectal cancer also has prognostic value.
Noci S et al. Pharmacogenomics J. 2015 May 12.
Noci S et al. Pharmacogenomics J. 2015 May 12.
Variations in genes involved in dormancy associated with outcome in patients with resected colorectal liver metastases.
Stremitzer S et al. Ann. Oncol. 2015 May 8.
Stremitzer S et al. Ann. Oncol. 2015 May 8.
A colorectal cancer prediction model using traditional and genetic risk scores in Koreans.
Jung Keum Ji et al. BMC Genet. 2015 (1) 49
Jung Keum Ji et al. BMC Genet. 2015 (1) 49
Association between polymorphisms in vascular endothelial growth factor gene and response to chemotherapies in colorectal cancer: A meta-analysis.
Wang L et al. PLoS ONE 2015 (5) e0126619
Wang L et al. PLoS ONE 2015 (5) e0126619
Familial colorectal cancer.
Lung MS et al. Intern Med J 2015 May (5) 482-91
Lung MS et al. Intern Med J 2015 May (5) 482-91
Next-generation sequencing panels for the diagnosis of colorectal cancer and polyposis syndromes: A cost-effectiveness analysis.
Gallego CJ et al. J. Clin. Oncol. 2015 May 4.
Gallego CJ et al. J. Clin. Oncol. 2015 May 4.
Genetic polymorphisms in cytochrome P450 and clinical outcomes of FOLFIRI chemotherapy in patients with metastatic colorectal cancer.
Dong N et al. Tumour Biol. 2015 May 2.
Dong N et al. Tumour Biol. 2015 May 2.
Screening in GI cancers: The role of genetics.
Stoffel EM et al. J. Clin. Oncol. 2015 Apr 27.
Stoffel EM et al. J. Clin. Oncol. 2015 Apr 27.
Clinical relevance of 8q23, 15q13 and 18q21 SNP genotyping to evaluate colorectal cancer risk.
Baert-Desurmont S et al. Eur. J. Hum. Genet. 2015 Apr 15.
Baert-Desurmont S et al. Eur. J. Hum. Genet. 2015 Apr 15.
Genomic Tests in Management of Colorectal Cancer - April 2, 2015
Costs and effectiveness of genomic testing in the management of colorectal cancer.
Goldstein DA et al. Oncology (Williston Park, N.Y.) 2015 Mar 15. (3)
Goldstein DA et al. Oncology (Williston Park, N.Y.) 2015 Mar 15. (3)
Genomic testing in colorectal cancer: How much is enough?
Dienstmann R et al, Oncology, March 2015
Dienstmann R et al, Oncology, March 2015
Cost-effectiveness of genomic testing for colorectal cancer: Are we there yet?
Barzi A et al. Oncology, March 2015
Barzi A et al. Oncology, March 2015
Aspirin: Genetics and Colorectal Cancer Risk - March 24, 2015
Precision medicine: Who benefits from Aspirin to prevent colorectal cancer? Francis Collins, NIH Director, Mar 24
Francis Collins, NIH Director, Mar 24
Association of Aspirin and NSAID use with risk of colorectal cancer according to genetic variants.
Nan H et al. JAMA 2015 Mar 17. (11) 1133-42
Nan H et al. JAMA 2015 Mar 17. (11) 1133-42
Aspirin and NSAID chemoprevention, gene-environment interactions, and risk of colorectal cancer.
Wender RC et al. JAMA 2015 Mar 17. (11) 1111-2
Wender RC et al. JAMA 2015 Mar 17. (11) 1111-2
Can Aspirin and cancer prevention be ageless companions?
Farag M et al. J Clin Diagn Res 2015 Jan (1) XE01-XE03
Farag M et al. J Clin Diagn Res 2015 Jan (1) XE01-XE03
P342. Meta-analysis: Does aspirin or non-aspirin non-steroidal anti-inflammatory drug use reduce colorectal cancer risk in patients with inflammatory bowel disease?
J Crohns Colitis 2015 Feb S250
J Crohns Colitis 2015 Feb S250
Impact of regular aspirin use on overall and cancer-specific survival in patients with colorectal cancer harboring a PIK3CA mutation.
Kothari N et al. Acta Oncol 2015 Apr (4) 487-92
Kothari N et al. Acta Oncol 2015 Apr (4) 487-92
Chemoprevention of colorectal cancer.
Lang M et al. Dig Dis 2015 (1) 58-67
Lang M et al. Dig Dis 2015 (1) 58-67
Molecular pathways: Aspirin and Wnt signaling-A molecularly targeted approach to cancer prevention and treatment.
Gala MK et al. Clin. Cancer Res. 2014 Dec 11.
Gala MK et al. Clin. Cancer Res. 2014 Dec 11.
Gene-environment interaction involving recently identified colorectal cancer susceptibility Loci.
Kantor D et al. Cancer Epidemiol. Biomarkers Prev. 2014 Sep (9) 1824-33
Kantor D et al. Cancer Epidemiol. Biomarkers Prev. 2014 Sep (9) 1824-33
Modulation of age- and cancer-associated DNA methylation change in the healthy colon by aspirin and lifestyle.
Noreen F et al. J. Natl. Cancer Inst. 2014 Jul (7)
Noreen F et al. J. Natl. Cancer Inst. 2014 Jul (7)
Aspirin and the risk of colorectal cancer in relation to the expression of 15-hydroxyprostaglandin dehydrogenase (HPGD).
Fink SP et al. Sci Transl Med 2014 Apr 23. (233) 233re2
Fink SP et al. Sci Transl Med 2014 Apr 23. (233) 233re2
Expression of HLA class I antigen, aspirin use, and survival after a diagnosis of colon cancer.
Reimers MS et al. JAMA Intern Med 2014 May (5) 732-9
Reimers MS et al. JAMA Intern Med 2014 May (5) 732-9
Genetic variation in UGT genes modify the associations of NSAIDs with risk of colorectal cancer: colon cancer family registry.
Scherer D et al. Genes Chromosomes Cancer 2014 Jul (7) 568-78
Scherer D et al. Genes Chromosomes Cancer 2014 Jul (7) 568-78
March is Colorectal Cancer Awareness Month - March 5, 2015
CDC information: Genetic testing for hereditary colorectal cancer
CDC information: Colorectal Cancer Awareness
CDC genomics and health information: Colorectal Cancer Awareness
Colorectal Cancer Screening & Prediction: Recent Genomic Insights - February 20, 2015
Role of tumour molecular and pathology features to estimate colorectal cancer risk for first-degree relatives.
Win Aung Ko et al. Gut 2015 Jan (1) 101-10
Win Aung Ko et al. Gut 2015 Jan (1) 101-10
Awareness and uptake of family screening in patients diagnosed with colorectal cancer at a young age.
Hogan Niamh M et al. Gastroenterol Res Pract 2015 194931
Hogan Niamh M et al. Gastroenterol Res Pract 2015 194931
A candidate gene study of capecitabine-related toxicity in colorectal cancer identifies new toxicity variants at DPYD and a putative role for ENOSF1 rather than TYMS.
Rosmarin Dan et al. Gut 2015 Jan (1) 111-20
Rosmarin Dan et al. Gut 2015 Jan (1) 111-20
Applicability of next generation sequencing technology in microsatellite instability testing.
Gan Chun et al. Genes (Basel) 2015 (1) 46-59
Gan Chun et al. Genes (Basel) 2015 (1) 46-59
A model to determine colorectal cancer risk using common genetic susceptibility loci.
Hsu Li et al. Gastroenterology 2015 Feb 12.
Hsu Li et al. Gastroenterology 2015 Feb 12.
The impact of stratifying by family history in colorectal cancer screening programs.
Goede S Lucas et al. Int. J. Cancer 2015 Feb 6.
Goede S Lucas et al. Int. J. Cancer 2015 Feb 6.
A stool DNA test (Cologuard) for colorectal cancer screening.
JAMA. 2014;312(23):2566.
JAMA. 2014;312(23):2566.
Preliminary validation of a consumer-oriented colorectal cancer risk assessment tool compatible with the US Surgeon General's My Family Health Portrait.
Feero WG, et al. Genet Med. 2014 Dec 18
Feero WG, et al. Genet Med. 2014 Dec 18
Potential of fecal microbiota for early‐stage detection of colorectal cancer.
Georg Zeller, et al. Molecular Systems Biology(2014)10:766
Georg Zeller, et al. Molecular Systems Biology(2014)10:766
Valuations of genetic test information for treatable conditions: the case of colorectal cancer screening
Kilambi V, et al. Value Health 2014 Dec;17(8):838-45
Kilambi V, et al. Value Health 2014 Dec;17(8):838-45
Clinical potential role of circulating microRNAs in early diagnosis of colorectal cancer patients.
Du M, et al. Carcinogenesis. 2014 Dec;35(12):2723-30.
Du M, et al. Carcinogenesis. 2014 Dec;35(12):2723-30.
Colorectal Cancer Screening: Stool DNA Screening Test - August 21, 2014
CDC information: Colorectal cancer screening tests
Multitarget stool DNA testing for colorectal-cancer screening
Imperiale T, et al. New England Journal of Medicine Mar 2014
Imperiale T, et al. New England Journal of Medicine Mar 2014
Public stated preferences and predicted uptake for genome-based colorectal cancer screening
Groothuis-Oudshoorn CG, et al. BMC Med Inform Decis Mak 2014 Mar;14(1):18
Groothuis-Oudshoorn CG, et al. BMC Med Inform Decis Mak 2014 Mar;14(1):18
Stool DNA and colorectal-cancer screening editorial
Robertson D, et al. New England Journal of Medicine Mar 19
editorialRobertson D, et al. New England Journal of Medicine Mar 19
Colorectal cancer screening: will non-invasive procedures triumph?
Timothy Church. Genome Medicine, June 2014
Timothy Church. Genome Medicine, June 2014
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