| SCF complexes are a class of E3 ubiquitination ligase that facilitate proteasomal degradation through the catalysis of ubiquitinylation. The cell cycle relies on ubiquitin and the SCF complex plays an integral role in the regulation of this process. | |
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| The researchers have used CRISPR to edit the genes of IVF embryos in a controversial attempt to create offspring that are resistant to disease. A team of researchers from the Southern University of Science and Technology in Shenzhen plans to eliminate a gene called CCR5 in an effort to ensure the babies are born resistant to HIV, smallpox and cholera. | |
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| In clathrin-mediated endocytosis, the cell membrane invaginates to take up metabolites, hormones, and proteins from the cell surface into intracellular vesicles. Cells employ several pathways for protein and lipid intake from the cell surface. These pathways include micropinocytosis, phagocytosis, and clathrin-mediated or caveolin-mediated endocytosis. | |
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| Transfection is a technique used to introduce foreign DNA into eukaryotic cells. Commonly, transfection is used to express a specific protein in cells, either transiently or permanently. | |
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| Being able to see these structures would allow an improved understanding of how cells function, but achieving this has been a difficult challenge. Until now, fluorescence microscopy has not provided a resolution high enough to observe the ultrastructure of these components. | |
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| Researchers have developed nanoscale “tweezers” that can extract cellular components such as DNA, proteins, and organelles, without causing damage or bursting the cell. | |
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