Dementia: Frailty Hastens It, Physical Activity Wards It Off
How is it that some people can have a brain full of plaques and tangles, yet somehow fend off dementia? By way of explanation, the concept of cognitive reserve tends to come up and now, two new postmortem studies suggest that physical fitness plays a role. In the February Lancet Neurology, researchers led by Kenneth Rockwood of Dalhousie University in Halifax, Nova Scotia, reported that people with plaques and tangles were more likely to have had dementia if they had also been frail. On January 16 in Neurology, researchers led by Aron Buchman at Rush University Medical Center in Chicago reported that being physically active correlated with better cognition, even in people with neurodegenerative pathology.
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