Extracellular vesicles are small vesicles that contain cytoplasmic and membrane components from their paternal cells. They enter target cells through uptake to transfer their biological cargo. In this study, the authors investigated the process of endothelial EV internalization and created a 3D visualization of their intracellular distribution. The 3D visualization allows the determination of a more accurate location of EVs relative to the donor cell nucleus.
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