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jueves, 5 de diciembre de 2019

Drug Discovery and Production | Medical News | Medical Articles | Drug Discovery and Production |

	Drug Discovery and Production
	The latest drug discovery news from News Medical

Why Ergonomic Pipetting in a Laboratory is Important

If you spent an hour sat at a laminar flow cabinet pipetting stacks of cell culture plates that needed to be passaged or fed, then once all of the plates were back in the incubator, you probably stretched your back to loosen the muscles that had tensed while you were working.

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The Facts and Considerations of Temperature Mapping

Temperature mapping is vital irrespective of how well constructed a storage area is, or a process is designed, as there will be temperature fluctuations that will affect the items being stored or processed. Controlled products such as food, medical devices and drugs are frequently subject to a greater degree of control and testing.

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Investigating Drug Penetration in Labskin

Using Matrix Assisted Laser Desorption Ionisation Mass Spectrometry Imaging (MALDI-MSI), the objective was to examine whether adding a penetration enhancer to a terbinafine product formulation can increase terbinafine penetration into Labskin.

	Cell death 'blocker' could speed recovery and save lives Scientists in Australia have shown that they can successfully stop the process of cell death through the use of a revolutionary new compound. This innovation carries huge implications that are likely to change the face of the future of healthcare, most notably, scientists believe they can develop this work to increase patient’s chances of survival following acute injury.

	Overview of Cell Viability and Cytotoxicity Measures of cell viability and cytotoxicity are essential for the development of new drug treatments for cancer. For a number of years, cell-based assays have been used to assess the impact of drugs on cell viability (the number of live cells), and the drug’s cytotoxicity (the toxic quality of the drug on the cells).

	High-performance Thin Layer Chromatography (HPTLC) in the Pharmaceutical Industry HPTLC is an extension of thin-layer chromatography (TLC). Thin-layer chromatography involves the separation of different components in a sample depending upon the relative affinity of each compound towards the stationary phase or mobile phase, while HPTLC helps in better resolution of compounds with lower limits of detection and quantifies separated components with the use of an integrated software platform.

	Custom-made oligonucleotide therapy for girl with fatal Batten disease Sufferers of fatal Batten disease have been given new hope as scientists develop a custom-made oligonucleotide therapy for a young girl. Doctors at Boston Children's Hospital met Mila Makovec in 2017. Mila had been diagnosed with incredibly rare Batten disease which is untreatable and fatal.

	What is Shotgun Lipidomics? Lipidomics refers to the study of cellular lipidomes, meaning the network of lipid constituents that maintain cellular and bodily health. Shotgun lipidomics follows these networks of lipids within biological systems on a larger scale, allowing identification, quantification, and interaction of lipids to be studied.