PARP - poly(ADP-ribose) polymerase (PARP) [NEW TOPIC PAGE]

https://phgkb.cdc.gov/GAPPKB/phgHome.do

From From Genomics & Health Impact Scan Database

This database includes published scientific literature on evidence-based translation of genomic discoveries into improved health care and disease prevention that have a potential impact on population health.

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• Phase III Trial of PARP Inhibitor Shows First Evidence of Improved Outcomes in Breast Cancer  
  Memorial Sloan Kettering, ASCO, June 4, 2017
• PARP inhibitors in ovarian cancer: evidence, experience and clinical potential.  
  Evans Tarra et al. Therapeutic advances in medical oncology 2017 Apr 9(4) 253-267
• Distinct implications of different BRCA mutations: efficacy of cytotoxic chemotherapy, PARP inhibition and clinical outcome in ovarian cancer.  
  Hollis Robert L et al. OncoTargets and therapy 2017 102539-2551
• The Role of BRCA2 Mutation Status as Diagnostic, Predictive, and Prognosis Biomarker for Pancreatic Cancer.  
  Martinez-Useros Javier et al. BioMed research international 2016 20161869304
• Delivering widespread BRCA testing and PARP inhibition to patients with ovarian cancer.  
  George Angela et al. Nature reviews. Clinical oncology 2016 Dec

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